Endocrine Abstracts

Introduction: Thyroid disorders such as subacute thyroiditis occur rarely in pregnancy. We report a recurrent case of subacute thyroiditis improved with the onset of pregnancy.Case report: A 32-year-old Turkish women who request pregnancy and planned insemination was referred due to malaise and neck pain in the left side a week ago. She was presented with low-grade fever, fatigue, pharingitis symptoms, neck pain and extremely tenderness in the right side...

Introduction: SIADH is frequently observed as a paraneoplastic secretion in many cancer types with the highest frequency described in small-cell lung cancer. The paraneoplastic secretion of ADH/vasopressin may induce hyponatraemia which is associated with increased morbidity and mortality. Conventional treatment of the condition consists of fluid restriction and demeclocycline. Tolvaptan, an oral V2-receptor antagonist, that directly targets the mechanism of SIADH, has been pr...

Introduction: Prolactinomas account for approximately 40% of all pituitary adenomas, with an estimated prevalence of 100 prolactinomas per million adults. Dopamine agonists currently represent the mainstay of treatment. Nevertheless, increasing dopamine-agonist dosage, surgery, and radiotherapy may be necessary in some cases, such as aggressive, dopamine-agonist resistant or atypical prolactinomas.Case: We report the case of a 55 year old man who was inc...

Osteoporosis in men is recently recognized as a major underestimated public health problem. In 2050, the incidence of hip fracture in men is expected to increase by 310% worldwide. After the age of 50, one out of three osteoporotic fractures are seen in men. Men suffering any major fracture have a higher mortality rate than women osteoporotic fractures. Screening is usually recommended in many guidelines above the age of 65 or 70 years and those younger aged with risk for oste...

Background: Diabetes is the commonest cause of ketoacidosis, with alcoholic and starvation ketoacidosis encountered less frequently. We present a case of high anion gap metabolic acidosis whose features were not categorigal for usual causes.Case presentation: A 42-year-old female patient was admitted with a 3 day history of nausea, vomiting and abdominal pain, that begun 1 day after binge alcohol intake, on the background of alcohol excess. AKI, transami...

PurposeObesity, diabetes mellitus, and metabolic syndrome (MetS) have been known to be associated with increased skin autofluorescence (SAF). In patients with MetS, higher SAF measurements were found to be associated with an increased number of the components of MetS. In this cross-sectional study, we aimed to evaluate the association of MetS and its’ components with skin autofluorescence in severely obese patients and to examine whether diabetes or...

Aim: To find out all Acromegalic patients above the age of 40 years had their colonoscopic screening or not.Reason for colonoscopy screening: There is 13 to 14 fold increased risk of colorectal cancer in Acromegaly patients and 2.5 fold increase in mortality from Colonic cancer.Standards: i) Patientts with acromegaly should be offered regular colonoscopy from the age of 40 years.ii) ...

Introduction: Hyperparathyroidism is uncommon during pregnancy with less than 200 cases reported worldwide. Untreated, this condition can result in a 20–30% incidence of fetal death and 50–60% incidence of complications during pregnancy. If recognized early, the condition is treatable with significant improvement in fetal and maternal outcomes.Case: We report the case of 35-year-old asymptomatic Asian female (gravida 9 para 4, one stillbirth) w...

Insulinoma is a rare but potentially treatable cause of hypoglycaemia. We present a case where achieving a diagnosis of insulinoma was complicated by evidence of low serum insulin levels during documented biochemical hypoglycaemia.A 58 year old lady presented with weight gain and daily episodes of shaking, hot flushes and disorientation that were relieved by the ingestion of food. During symptomatic episodes home capillary blood glucose measurements sugg...

Patients and methods: 190 acromegalic patients are registered in the National Diabetes Center, 60 were enrolled in the study. They were randomly selected by simple sampling technique according to their scheduled visits monthly to receive - long acting repeatable octreotide injections (LAR).Results: Table 1 Demographic data of the enrolled acromegalic patients.</c...