Endocrine Abstracts

Introduction: Diabetic peripheral neuropathy (DPN) is a frequent complication of diabetes mellitus. The aim of our work is to determine the prevalence as well as the predictive factors of this degenerative complication and as a secondary endpoint the evaluation of the risk factors associated with painful diabetic neuropathy.Methods: This is a retrospective and prospective cross-sectional study with descriptive and analytical aims conducted over a period ...

Introduction: Stiff-Person Syndrome (SPS) is a rare autoimmune neurological disorder that can be associated with other autoimmune diseases including type 1 diabetes mellitus (T1DM). The presence of alternative forms of autoimmune diabetes, such as latent autoimmune diabetes in adults (LADA) in SPS, is not well described.Case Report: A 63 years old male patient, his medical and family histories were non-specific. He developed progressive rigidity in trunc...

Introduction: Centropontic myelinolysis (CPM) is a neurological pathology related to axonal demyelination lesions, often localized at the pontine level. For a long time, this condition was attributed to rapid correction of hyponatremia. A few cases of PCM with normal natraemia have been described, in a context of undernutrition, chronic alcoholism, hypokalaemia or hyperglycaemia.Patient and observation: We report the case of an 18 years old patient, type...

Introduction: Angiosarcomas are aggressive malignant tumors but very rare especially when they are located in the thyroid, characterized histologically by their vascular differentiation and their polymorphic appearance.Observation: We report the case of a 68-years-old female patient, from a mountainous region who has a history of cholecystectomy in 2018, she underwent a total thyroidectomy for a compressive goiter, the postoperative period was marked by ...

Introduction: Acromegaly is an unusual endocrinopathy due to hypersecretion of growth hormone (GH) and concomitant rise of IGF-1. It is associated with premature of mortality caused by cardiovascular, respiratory and metabolic diseases, as well as increased risk of developing boh benign and malignant tumours. We report the case of a patient with acromegaly associated with papillary thyroid microcarcinoma (PTC).CASEA 50-years -old m...

Introduction: Cushing’s disease is characterized by an endogenous hypercortisolism related to a pituitary adenoma, its association with an empty sella turcica is exceptionally rare.Case report: A 55 year old diabetic patient with hypertension was admitted for investigation of Cushing’s syndrome. Clinical examination found facial and truncal obesity with facial erythrosis, capillary fragility with multiple ecchymoses, proximal amyotrophy of the ...

Introduction: Pituitary stalk interruption syndrome (PSIS) is a distinct developmental defect characterized by a thin or absent pituitary stalk, hypoplasia of the adenohypophysis, and ectopic location of the neurohypophysis.Case report: A 36 years old male patient, full term born by vaginal delivery, with birth asphyxia. Birth weight was 2800 g, length was 51 cm, and no other postnatal events were noticed. Psychomotor milestones were achieved normally. h...

Introduction: Noonan syndrome (NS) is an autosomal dominant genetic disorder characterized by the combination of facial dysmorphia, short stature and congenital heart disease. The mutation of the PTPN11 gene is present in 50% of cases, recently the mutation of other genes was found, notably KRAS and SOS1. We report the case of a patient followed in our department for NS with a SOS1 gene mutation.Case report: A 4 years old male patient, referred to our de...

Introduction: Sheehan’s syndrome or Simmond’s disease is a partial or complete postpartum hypopituitarism caused by pituitary infraction and necrosis that usually occurs as a complication of massive postpartum hemorrhage or severe hypotension during or after labor and delivery. We present the case of Sheehan’s syndrome presenting postpartum depression. Case: A 40 years old woman, referred to our department by her psychiatrist for explorati...

Introduction: Celiac disease (CD) is an autoimmune enteropathy, induced by dietary gluten in genetically predisposed subjects, which manifests itself, most often, by digestive signs but also extra-digestive signs, in particular failure to thrive (FTT), nevertheless it is necessary to remain vigilant with regard to a real associated somatotropic deficit.CASE: A 14-years-old male patient, followed for a celiac disease since the age of 6 years, under a stri...