Endocrine Abstracts

Introduction: Sex hormones, such as estrogens or progesterone may have, both directly and indirectly, an influence on the appetite changes in. In addition, exogenous sex hormones are commonly used as one method of contraception.Aim: The purpose of this study was to assess whether the eating style in a group of menstruating women, taking oral hormonal contraceptives, is different in the individual menstrual cycle phases.Material and...

Background: Hyperandrogenism in congenital adrenal hyperplasia (CAH) is associated with virilisation in female patients and subfertility in both male and female patients. However, little is known regarding the association of hyperandrogenaemia with polycythaemia. We evaluate the association between the adrenal hormone profile and haematocrit (HCT)/haemoglobin (Hb) in a cohort of patients with classical CAH.Methods: Single centre retrospective analysis of...

Method: We carried out a retrospective audit of baseline data for patients under our care with primary hyperparathyroidism on cinacalcet therapy, against the NHS England Clinical Commissioning Policy (July 2016). Patients with secondary hypercalcaemia due to end stage renal failure were excluded.Results: 40 patients were identified, 9 men and 31 women, with an age range of 32–89 years (median age 78). 3 patients were under 50 ...

Method: We carried out a retrospective audit of baseline data for patients under our care with primary hyperparathyroidism on cinacalcet therapy, against the NHS England Clinical Commissioning Policy (July 2016). Patients with secondary hypercalcaemia due to end stage renal failure were excluded.Results: 40 patients were identified, 9 men and 31 women, with an age range of 32–89 years (median age 78). 3 patients were under 50 ...

A male with classical salt-wasting congenital adrenal hyperplasia (CAH; 21-hydroxylase deficiency) who was diagnosed in infancy and had normal pubertal growth and development attended the endocrine department for routine follow up in June 2019 (age 26). His current daily medications are hydrocortisone 10 mg on waking, 5 mg at 4 pm and fludrocortisone 200 mg once daily. He also has injectable hydrocortisone sodium phosphate 100mg for emergency use. Over recent years, he reports...

Pseudohypoparathyroidism (PHP) is a group of rare hereditary diseases caused by tissue resistance to parathyroid hormone (PTH), there are two main types I and II. Type I is divided into subtypes. The authors present a case of PHP Ib, with hypocalcemia (level of total calcium 1.41 mmol/l), accidentally detected at childbirth. After the unsuccessful treatment of hypocalcemia, the etiology was considered, but the confirmation of the diagnosis were not adequately tightened. Due to...

The conducted national screening of Bulgarian pregnant women showed a frequency of Hyperglycemia among them of 14.4%. It is known that a number of factors have a significant impact on this disorder. The aim: to assess risk factors for the development of Hyperglycemia in pregnant women in Bulgaria.Material: We screened 547 pregnant women, mean age 30.49±5.12 years, divided into two groups: up to 24 gestational week –g.w. (n-386, 70.6%) and after 2...

Introduction: Renin angiotensin system play a crucial role in the development of Diabetes Mellitus and its complications. According many studies, plasma renin level increased at the DM. However, mechanisms of its elevation is not clear yet. The aim of our study was compare plasma renin level in DM1 and DM2 patients and its relationship with glycemic control.Material and Methods: In 44 people with DM1 and 85 with DM2 whose admitted into Hospital of the Re...

A 36-year-old man from Romania was referred to the urology clinic with a two-year history of a painful left testicular swelling. On examination, both testes had multiple solid non-tender masses. An ultrasound scan of the testes showed bilateral, symmetrical infiltration of both testes, with scattered calcifications and enhanced blood flow. The differential diagnosis included testicular cancer, granulomatous diseases, leukaemia and adrenal rests. A CT scan showed no metastatic/...

We present two cases of alternative approaches to treating endocrine disease. Case 1: A 55-year-old man became steroid dependent in 2017, following a skiing accident and C3/4 fracture, for which he received 13-months of high-dose hydrocortisone. Upon cessation, he developed adrenal crisis, confirmed on short synacthen test. Hydrocortisone replacement therapy was begun. His dose was doubled, then tripled to control his symptoms, in addition to frequent re...