Endocrine Abstracts

Objective: To compare 2 modalities of bolus-basal insulin therapy with aspart-detemir, according to the moment of administration of detemir (DET), before the lunch or bed-time, in type 1 diabetic patients with poor metabolic control.Methods: We conducted a prospective study of 40 type 1 diabetic patients, with poor metabolic control (HbAc 7–12%), randomized to receive treatment with 1 injection of DET before the lunch or bed-time and followed-up dur...

Objectives: We have examined the relationship between the hepatic enzymes and type 2 diabetes. We have analyzed if the levels of hepatic enzymes are associated with body weight, lipid profile and the treatment with metformin, thiazolidinediones or statins.Methods: 318 patients with type 2 diabetes were included and they were compared with 100 healthy subjects. Alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gammaglutamiltranspeptidas...

IntroductionNon-functioning secretory pituitary adenomas are usually characterized by the lack of associated hormone overproduction. The absence of symptoms of excess hormone production results in a delayed diagnosis: sometimes as an incidental diagnosis, sometimes due to compressive symptoms with visual involvement or neurological symptoms as headache. Howewer, hydrocephalus associating Hakim-Adams Syndrome caused by foramen of Monro obstruction seconda...