Searchable abstracts of presentations at key conferences in endocrinology

ea0034p318 | Reproduction | SFEBES2014

Plant molecules quercetin and resveratrol can affect ovarian cells and invert FSH action

Stochmalova Aneta , Kadasi Attila , Alexa Richard , Sirotkin Alexander

Quercetin and resveratrol, powerful antioxidants and blockers of intracellular mTOR signalling system, are widely distributed in edible plants. Their action on ovarian cell functions and the interrelationships with gonadotropin are studied insufficiently. We examined the effect of FSH, quercetin, resveratrol and their combinations on proliferation and apoptosis of cultured porcine ovarian granulosa cells. Accumulation of marker of proliferation (PCNA) and marker of apoptosis (...

ea0038p370 | Reproduction | SFEBES2015

Food, drink and medical plants and their molecules can affect female hormones and reproductive functions

Sirotkin Alexander V , Kadasi Attila , Stochmalova Aneta , Alexa Richard , Balazi Andrej , Harrath Abdel Halim

The aim of our studies was to examine the effect of some food, drink and medical plants and their molecules on female ovarian endocrine and other functions in vitro and in vivo. We analysed the effects of plant (green tea, rooibos, ginkgo, flaxseed, chia, yukka) extracts and plant substances (green tea polyphenols, green tea epigallocatechin-3-gallate, curcumin, resveratrol, diadzein and diosgenin) on the release of hormones and markers of proliferation, apop...

ea0034p348 | Steroids | SFEBES2014

The effect of green tea extracts on steroidogenesis, proliferation and apoptosis in ovarian granulosa cells

Kadasi Attila , Maruniakova Nora , Kolesarova Adriana , Stochmalova Aneta , Alexa Richard , Grossmann Roland , Sirotkin Alexander V

The aim of our study was to examine the influence of green tea molecules on basic ovarian functions. For this purpose we have examine the effect of green tea extract, fraction of antioxidants (GTAO) and green tea fraction of polyphenols (GTPP) (at the doses 0, 1, 10, and 100 μg/ml) on proliferation, apoptosis, and steroidogenesis by cultured porcine ovarian granulosa cells. Markers of proliferation (PCNA) and apoptosis (bax) were detected by immunocytochemistry. Secretion...