Endocrine Abstracts

We describe a 40-year-old female who presented with fine tremors, weight loss, dyspnea and hemoptysis. On examination she appeared diaphoretic and tachycardic without goiter or thyroid eye disease. Thyroid function tests confirmed biochemical hyperthyroidism: [fT4 >100 pmol/l (NR: 12–22), TSH <0.005 mu/l (NR: 0.270–4.200)]. Chest X-ray showed numerous metastatic pulmonary nodules bilaterally. CT chest confirmed multiple large pulmonary metastases throughout both ...

Graves’ disease is an autoimmune disorder of the thyroid gland. Patients with type 1 diabetes (T1DM) are at a higher risk of developing autoimmune diseases including thyroid disorders. To our knowledge, diagnosing Graves’ disease at the same time in a monozygotic twin with T1DM is a rare occurrence. We present a case of monozygotic female twin with T1DM, who both developed Graves’ disease at the same time. Type 1 diabetes was diagnosed in one of the twins (twin ...

Introduction: Iatrogenic Cushing’s syndrome (ICS) can be caused by virtually all forms of steroid treatment with or without suppression of hypothalamic–pituitary–adrenal (HPA) axis. Here we report betamethasone nasal drops used as treatment post septorhinoplasty as a cause of iatrogenic Cushing’s syndrome.Case: A 36 years old female with background history of depression presented to endocrinology clinic for evaluation of progressive w...

Introduction: Pituitary tuberculosis (TB) is a rare form of intracranial TB and remains a diagnostic challenge in the absence of systemic TB. A limited number of cases has been reported in the literature.Case: A 47-year-old south Asian man presented to the accident and emergency department with complete isolated left third nerve palsy which had developed gradually over the course of a week. Brain magnetic resonance imagining (MRI) revealed a 15 mm inflam...

Introduction: Thyrotroph pituitary hyperplasia in context of severe primary hypothyroidism is rare and usually occurs due to loss of thyroxine feedback inhibition and overproduction of thyrotropin-releasing hormone, leading to pituitary gland enlargement. Pituitary hyperplasia caused by primary hypothyroidism responds well to thyroid hormone replacement therapy and rarely requires surgical intervention. Case presentation: A 42-year-old female with backgr...

Introduction: Acromegaly is commonly associated with numerous cardiovascular manifestations such as left ventricular hypertrophy, hypertension and ischemic heart disease. However, initial presentation with dilated cardiomyopathy is relatively rare. Dilated cardiomyopathy in patients with acromegaly usually result from an extended and excessive exposure of the myocardium to growth hormone.Case presentation: 51-year-old female with background medical histo...

Introduction: Bariatric surgery (BS) is currently the most effective treatment for obesity. However, weight regain is a recognized challenge in post-surgical management. Drug treatment for weight regain after bariatric surgery has been used, but little published data is available on their efficacy. We have investigated the use of Liraglutide for relapse after BS in an Emirati population.Methods: ICLDC patients with a previous history of bariatric surgery...