Endocrine Abstracts

33-year old obese but otherwise considered ’healthy’ patient was admitted to department of surgery due to wet gangrene of left foot. Lower leg amputation was done. As patient was obese with ITM 44 kg/m2 endocrinologist was consulted. In overnight 1 mg dexamethason supression test cortisol was 72 nmol/l, HbA1c was 5.7%, TSH was 8 mIU/l, level of 25-OH D vitamin below lower range and arterial blod pressure was normal (130/80 mmHg). Patient had central obesit...

78-year old previously healthy man was reffered to Outpatient endocrinology clinic due to painful spine and shoulders. His lumbar and thoracic X-ray showed decreased lumbar and thoracic vertebrae (L1, L2 and Th 5) and densitometry indicated slightly decreased bone density with T score -1,0 in left femoral neck and L1 vertebra. Since patient mentioned recent unintentionally 10 kg weight loss he was processed to further work-up and additional blood tests were done. Secondary ost...

Background: Amiodarone is a commonly used antiarrhythmic drug, but because of its abundance with iodine and a direct toxic effect on the thyroid, it can have side effects like hypo- and hyperthyroidism. There are two types of amiodarone-induced thyrotoxicosis (AIT). We present a case which demonstrates the importance of timely diagnosis and appropriate treatment of amiodarone-induced thyrotoxicosis in patients with serious cardiac comorbidities.Case pres...

Pheochromocytomas are rare catecholamine-producing tumors that arise from chromaffin cells located in the adrenal medulla. They are usually benign, but approximately 10% of pheochromocytomas are malignant. The most common clinical features include Menard triad: headache, sweating and palpitations, and permanent or paroxysmal hypertension. Haematuria as a presenting feature of adrenal pheochromocytoma is rarely seen. We report a case of pheochromocytoma in a 61-year-old female ...

We present a case of a 70-year-old female patient without comorbidities who was admitted to our institution following head trauma leading to subsequent subarachnoid hemorrhage and vertigo. Conservative management was implemented successfully. Throughout the hospitalization, lab monitoring revealed the emergence of hyponatremia which was corrected by fluid restriction and hypertonic solution administration. The patient was discharged without residual vertiginous complications. ...

Background: Medullary thyroid cancer is a rare neuroendocrine neoplasm that can secrete variety of hormones, including ACTH. Cushing syndrome due to ectopic ACTH secretion is a rare complication of medullary thyroid cancer, usually accociated with metastatic disease. Around 50 percent of patients with medullary thyroid carcinoma and ectopic Cushing syndrome die due to complications of hypercortisolism. Based on the aforementioned, efficient management of hypercortisolism is cr...