Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep859 | Late Breaking | ECE2021

Infertility revealing a classical form of congenital adrenal hyperplasia in a 39 years old man

Alassane Ilboudo , Yempabou Sagnan , Mathilde Guigui , Sophie Dubreuil , Antonin Lamaziere , Bachelot Anne , Touraine Philippe , Carine Courtillot

Classical forms of congenital adrenal hyperplasia (CAH) are generally diagnosed in neonates (salt wasting form) or in early childhood (pure virilizing form). Here, we report the case of a 39 years old man from Sri Lanka in whom a classical CAH has been diagnosed during the exploration of infertility with azoospermia, along with extremely low gonadotropins contrasting with a normal level of testosterone. Hormonal tests revealed high serum 17-hydroxyprogesterone levels (255 ng/m...

ea0049gp19 | Adrenal 2 | ECE2017

Plasma cortisol and aldosterone responses to insulin tolerance test and sodium depletion in women with non classic 21-hydroxylase deficiency caused by bi-allelic CYP21A2 mutations (NC-CAH)

Kamenicky Peter , Blanchard Anne , Lamaziere Antonin , Donadille Bruno , Duranteau Lise , Salenave Sylvie , Pietri Laurence , Raffin-Sanson Marie Laure , Gautier Jean-Francois , Chanson Philippe , Maitre Sophie Christin , Tardy Veronique , Bouc Yves Le , Brailly-Tabard Sylvie , Young Jacques

NC-CAH is diagnosed in pubertal/post-pubertal women because of androgen excess however, the risk of potential adrenal insufficiency is not known, and indication of systematic glucocorticoid replacement therapy is controversial.Design: Prospective controlled clinical study in a tertiary referral center. 20 women with NC-CAH (serum stimulated 17-OHP >10 ng/ml/250 μg, Synacthen) comparatively to matched healthy women, were included if they had not ...