Searchable abstracts of presentations at key conferences in endocrinology

ea0063p640 | Interdisciplinary Endocrinology 1 | ECE2019

Different regulation of erythropoietin and VEGF in clear renal cell carcinoma

Cokic Bojana Beleslin , Macut Djuro , Milicevic Ivana , Rodic Gordana , Bankovic Jovana , Antic Jadranka , Noguchi Constance , Damjanovic Svetozar

Clear renal cell carcinoma (ccRCC) is a highly vascularized and proliferative tumor. ccRCC can be sporadic or familiar, usually associated with von Hippel-Lindau (VHL) gene mutations. VHL protein is part of the E3 ubiquitin ligase complex that regulates hypoxia-inducible factor (HIF). When a defective and inactive VHL protein is produced, HIF is not degraded, resulting in over-expression of hypoxia related genes including erythropoietin (EPO) and vascular endothelial growth fa...

ea0049ep166 | Endocrine tumours and neoplasia | ECE2017

Clinical characteristics and survival of patients with paraganglioma: a single center experience

Elezovic Valentina , Macut Djuro , Ognjanovic Sanja , Isailovic Tatjana , Popovic Bojana , Bozic-Antic Ivana , Bogavac Tamara , Ilic Dusan , Bankovic Jovana , Damjanovic Svetozar

Paragangliomas (PGLs) and pheochromocytomas (PCCs) are rare neuroendocrine tumors that derived from pluripotent neural crest stem cells. PCCs are derived from the adrenal medulla, while PGLs are histologically identical tumors derived from ganglia outside the adrenal gland. Even though the majority of tumors are benign, they are associated with high morbidity rates caused by excessive catecholamine secretion. We retrospectively analyzed 71 patients (36 female and 35 males) wit...