Searchable abstracts of presentations at key conferences in endocrinology

ea0035p772 | Obesity | ECE2014

Offspring of parents with obesity complex investigations: risk of carbohydrate disturbances and diabetes

Dziura Maria , Basiak Aleksander , Wasikowa Renata Barbara

Aim of the study: To examine offspring of patients with simple obesity. To ascertain, if there are some disturbances in the carbohydrate or lipid metabolism or unknown type 2 diabetes in these subjects.Method and subjects: Examined were 132 families, 108 families with obesity, and 24 families without obesity, the control group. Fourteen additional were excluded because of ascertained at the time of examination unknown type 2 diabetes in the parents. In a...

ea0037ep344 | Diabetes (pathiophysiology & epitemiology) | ECE2015

The GH treatment results in the increase of irisin concentration in plasma

Wikiera Beata , Pukajlo Katarzyna , Laczmanski Lukasz , Sloka Natalia , Basiak Aleksander , Bolanowski Marek , Noczynska Anna , Daroszewski Jacek

Brown adipose tissue metabolism is of remarkable pathophysiological interest, because it could be a target for future therapies for obesity and metabolic syndrome. Irisin (Ir), recently identified novel adipomyokine is essential in a white-to-brown fatty tissue transdifferentiation, and mediates some of the positive influences on metabolic disorders through increase of energy expenditure. The exact regulation of Ir secretion and action is unknown but significant positive assoc...