ea0020p685 | Signal Transduction | ECE2009
, Renko Kostja
, Behrends Thomas
, Schomburg Lutz
Many endocrine disorders bear an immunological component and involve local cytokines as paracrine signals. Moreover, certain auto-antibodies appear as causative pathological agents in some of the most common endocrine diseases e.g. in type I diabetes mellitus or different forms of autoimmune thyroid disease (AITD). Recently, selenium (Se) status and selenoproteins have emerged as important modifiers of the inflammatory response, AITD or sepsis. Notably, mortality risk of patie...