Searchable abstracts of presentations at key conferences in endocrinology

ea0026p648 | Clinical case reports | ECE2011

How differentiated can a poorly differentiated thyroid cancer be? A rare case presenting with hyperthyroidism and secondary adrenal insufficiency

Melo M , Carrilho F , Ribeiro C , Carvalheiro M

Introduction: Poorly differentiated thyroid cancers are usually aggressive tumors that lack many of the characteristics of differentiated thyroid tissue, including the ability to uptake and process iodine.Case report: A 75-year-old male presented with weight loss, tiredness, asthenia, tremor, increased perspiration, tachycardia and bone pain in several locations. A hard and fixed thyroid nodule was palpable in the left lobe (FNA-«follicular tumor&#1...

ea0029p466 | Clinical case reports - Thyroid/Others | ICEECE2012

Ectopic Cushing’s syndrome and thymic hyperplasia

Vieira A. , Paiva I. , Alves M. , Gouveia S. , Saraiva J. , Moreno C. , Carrilho F. , Carvalheiro M.

Introduction: Thymic hyperplasia has been described after hypercortisolism resolution. The natural history remains poorly defined: emergence ≧1 month after hypercortisolism resolution, variable duration, usually spontaneous resolution/benign course.Case Report: ♂, 24, referred in 2000 for secondary hypothyroidism: TSH: 0.25 μUI/ml (0.25–5); FT4: 5.55 pmol/l (9–20). Clinical evaluation: insomnia, nocturnal sweating, facial eryt...

ea0026p451 | Thyroid cancer | ECE2011

Recombinant tsh-stimulated thyroglobulin measurements in patients with differentiated thyroid carcinoma with basal thyroglobulin <1 ng/ml

Vieira A , Carrilho F , Ribeiro C , Melo M , Alves M , Gouveia S , Saraiva J , Carvalheiro M

Introduction: A value of thyroglobulin (Tg) undetectable under treatment with levothyroxine (LT) does not exclude residual/metastatic disease; this can be found in 18–35% of patients after recombinant TSH-stimulated Tg (sTg) measurements.Objective: Evaluating the role of recombinant TSH-stimulated thyroglobulin (sTg) measurements in patients with differentiated thyroid carcinoma, treated with suppressive LT doses, with basal Tg (bTG)<1 ng/ml.</p...

ea0026p588 | Clinical case reports | ECE2011

Congenital adrenal hyperplasia and adrenal myelolipoma -- incidental ou causal relationship?

Vieira A , Paiva I , Santos J , Alves M , Gouveia S , Saraiva J , Carrilho F , Carvalheiro M

Introduction: There are fewer than 20 reported cases involving congenital adrenal hyperplasia (CAH) and myelolipoma. This is a rare benign tumor, often located on the adrenal, consisting of mature adipose and hematopoietic tissues. Its origin is unclear; the most accepted theory is the occurrence of blood capillaries reticuloendothelial cells metaplasia, in response to infection, stress or necrosis. In a small number of cases ACTH hypersecretion coexists.<p class="abstext"...

ea0040p18 | (1) | ESEBEC2016

Massive bilateral pheocromocitomas: a rare case

Martins D , Baptista C , Rodrigues D , Miguel Melo , Cardoso L M , Vicente N , Oliveira D , Ventura M , Lages A , Carrilho F

Introduction: Pheochromocytoma is a rare catecholamine-secreting tumor that arises from the chromaffin tissue of the adrenal medulla. Of the reported cases, only 10% consist in bilateral lesions and the probability of multiple endocrine neoplasia should always be investigated.Clinical case: Female patient, 19 years old, presented with a clinical history with 2 years of evolution, characterized by episodes of palpitations, headache, nausea and abdominal d...

ea0029p719 | Diabetes | ICEECE2012

Continuous subcutaneous insulin infusion systems: experience in 92 patients with type 1 diabetes

Saraiva J. , Carrilho F. , Barros L. , Batista C. , Melo M. , Gomes L. , Vieira A. , Alves M. , Gouveia S. , Moreno C. , Carvalheiro M.

Background: Continuous subcutaneous insulin infusion (CSII) using an external pump is an alternative intensive diabetes therapy recognized to improve metabolic control and glycemic instability in selected type 1 diabetic (T1DM) subjects. The aim of this study was to examine the clinical effectiveness and safety of CSII systems over a 5-year follow-up period in T1DM patients.Materials and methods: We performed a retrospective observational study of T1DM p...

ea0026p484 | Thyroid cancer | ECE2011

Seventh UICC/TNM staging criteria for medullary thyroid carcinoma: is there any prognostic advantage?

Martinho M , Azevedo T , Carrilho F , Martins T , Ribeiro C , Melo M , Cunha N , Rascao M J , Neves A , Gilde P , Pires J L , Cruz C , Oliveira C , Neto J , Oliveira S , Valido F , Gomes I , Carvalheiro M , Rodrigues F

Background and aims: The value of the revised (2009) UICC/TNM criteria for medullary thyroid cancer (MTC) is not established. We aimed to evaluate its predictive value, analyzing the consequences of the inclusion of T3N0M0 patients previously included in stage III of the 6th edition, in stage II of the 7th.Patients and methods: We retrospectively analysed the clinical records of 85 patients operated for MTC and followed in two tertiary hospitals in the c...