Searchable abstracts of presentations at key conferences in endocrinology

ea0029p289 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012

Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study

Rastrelli G. , Corona G. , Monami M. , Guay A. , Buvat J. , Sforza A. , Forti G. , Mannucci E. , Maggi M.

Objective: To verify whether hypogonadism represents a risk factor for cardiovascular (CV) morbidity and mortality and to verify whether testosterone replacement therapy (TRT) improves CV parameters in subjects with known CV diseases (CVDs).Design: Meta-analysis.Methods: An extensive Medline search was performed using the following words ‘testosterone, CVD, and males’. The search was restricted to data from January 1, 196...

ea0029p1024 | Male Reproduction | ICEECE2012

Inhibitors of 5α-reductase-related side effects in patients seeking medical care for sexual dysfunction

Rastrelli G. , Corona G. , Maseroli E. , Sforza A. , Forti G. , Mannucci E. , Maggi M.

Introduction: Despite their efficacy in the treatment of benign prostatic hyperplasia (BPH) the popularity of inhibitors of 5α-reductase (5ARIs) is limited by their association with adverse sexual side effects. However, the real impact of 5ARIs on sex hormones and sexual function is controversial.Aim: The aim of this study is to investigate the role of 5ARIs therapy on hormonal parameters and sexual function in men already complaining of sexual prob...

ea0029p1039 | Male Reproduction | ICEECE2012

Poor response to alprostadil ici test is associated with arteriogenic erectile dysfunction and higher risk of major adverse cardiovascular events

Rastrelli G. , Corona G. , Monami M. , Melani C. , Balzi D. , Sforza A. , Forti G. , Mannucci E. , Maggi M.

Introduction: Intracavernous alprostadil injection (ICI) test has been considered useless in assessing the vascular status of subjects with erectile dysfunction (ED).Aim: To analyze the clinical correlates of ICI test in patients with ED and to verify the value of this test in predicting major adverse cardiovascular events (MACE).Methods: A consecutive series of 2,396 men (mean age 55.9±11.9 years) attending our outpatient cli...

ea0029p1040 | Male Reproduction | ICEECE2012

Hormonal associations and sexual dysfunctions in patients with impaired fasting glucose

Rastrelli G. , Corona G. , Balercia G. , Lotti F. , Sforza A. , Monami M. , Forti G. , Mannucci E. , Maggi M.

Introduction: The category of impaired fasting glucose (IFG) denotes a state of non-diabetic hyperglycemia, considered a risk factor of the further development of diabetes mellitus (DM) and cardiovascular (CV) diseases.Aim: The aim of the present study is to evaluate the impact of IFG on sexual health in men. In addition its effect on CV morbidity and mortality will also be addressed.Methods: A consecutive series of 3451 men (mean ...

ea0029p290 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012

Testosterone and cardiovascular risk in patients with erectile dysfunction

Corona G. , Rastrelli G. , Balercia G. , Sforza A. , Forti G. , Maggi M.

Background: The relationship between cardiovascular (CV) diseases (CVD) and testosterone levels in men has not been completely clarified.Aim: To evaluate the association between testosterone levels and CV risk in subjects with erectile dysfunction (ED) and to verify whether their body mass index might (BMI) represents a possible confounder in testosterone-related CV stratification.Material and methods: A consecutive series of 2269 ...

ea0029p1042 | Male Reproduction | ICEECE2012

Premature ejaculation and erectile dysfunction in a cohort of infertility men: clinical and ultrasonographic correlations

Lotti F. , Corona G. , Rastrelli G. , Forti G. , Jannini E. , Maggi M.

Introduction: Premature ejaculation (PE) and erectile dysfunction (ED) are considered pre-testicular causes of male subfertility. No previous study systematically evaluated the prevalence of ED and PE along with their possible correlations with clinical and colour-Doppler ultrasound (CDU) features in infertile men.Methods: Ejaculatory status, erectile function, prostatitis symptoms and psychopathological traits of 244 men complaining of couple infertilit...

ea0029p1044 | Male Reproduction | ICEECE2012

Scrotal and transrectal ultrasound correlates of prostatitis-like symptoms in a cohort of infertility patients

Lotti F. , Corona G. , Filimberti E. , Innocenti SDegli , Forti G. , Maggi M.

Introduction: Prostatitis-like symptoms (PLS) may originate from the prostate or from pelvic or scrotal organs. The National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) is considered the gold-standard instrument to assess PLS severity. Although several studies previously investigated the impact of prostatitis, vesiculitis or epididymitis on semen parameters, only a few studies evaluated the correlations between PLS and scrotal or transrectal colour-Dopple...

ea0029p1553 | Steroid metabolism + action | ICEECE2012

The role of long-acting parenteral testosterone undecanoate compound (Nebid 1000 mg) in the induction of secondary sexual characteristics (SSC) in males with hypogonadotropic hypogonadism (HH)

Giagulli V. , Triggiani V. , Corona G. , Tafaro E. , Licchelli B. , Guastamacchia E.

Testosterone (T) can induce SSC in young HH men. So far the T ester formulations have been used for inducing puberty in these patients. Moreover, it seems that the polymorphism CAG length of androgen receptor (AR-CAG) might co-regulate the effectiveness of testosterone therapy (Tth).This study aims to evaluate the effectiveness of Nebid (1000 mg) for SSC induction in HH men and, secondly, whether these changes might be modulated by the AR-CAG.<p clas...

ea0011p653 | Reproduction | ECE2006

Psycho-biological correlates of free-floating anxiety symptoms in male patients with sexual dysfunctions

Corona G , Mannucci E , Petrone L , Ricca V , Balercia G , Giommi R , Forti G , Maggi M

Introduction and objectives: Anxiety has a relevant impact on everyday life, including sexual life, and therefore is considered the final common pathway by which social, psychological and biological stressors negatively affect sexual functioning. The aim of this study is to define the psycho-biological correlates of free-floating anxiety in a large sample of patients complaining erectile dysfunction (ED) based sexual problems.Methods: We studied a consec...