Searchable abstracts of presentations at key conferences in endocrinology

ea0029s3.3 | Absolute fracture risk assessment with FRAX | ICEECE2012

Beyond FRAXÒ

Eisman John A.

The FRAXÒ algorithm represented a major step forward in absolute fracture risk assessment. It took advantage of globally derived information to predict fracture risk that used that as the basis for rational treatment recommendations for a large proportion of the international community. The extrapolation of FRAXÒ to different regional and geographic criteria has been based on two sets of data that can be obtained with relatively high accuracy; these being regional ag...

ea0081rc5.6 | Rapid Communications 5: Diabetes, Obesity, Metabolism and Nutrition 2 | ECE2022

Effects of bariatric surgery and dietary intervention on changes in insulin resistance and appetite hormones over the period of 3 years

Brzozowska Malgorzata , Isaacs Michelle , Bliuc Dana , Baldock Paul , Eisman John , White Chris , Greenfield Jerry , Center Jacqueline

Objectives: Little is known about the mechanisms responsible for improvement in insulin resistance after bariatric surgery. We examined the impact of three types of bariatric surgery, in comparison with dietary intervention (DIET) on concurrent changes in Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) and appetite hormones over the period of 3 years. We also investigated the weight loss independent hormonal effects on insulin resistance.Me...

ea0035p748 | Obesity | ECE2014

Bariatric surgery and bone loss: novel mechanisms and comparison of different modalities

Brzozowska Malgorzata , Bliuc Dana , Hong Angel , Jorgensen John , Talbot Michael , Rigas Georgia , Chen Weiwen , Pocock Nicholas , Eisman John , White Christopher , Baldock Paul , Center Jacqueline

Although bariatric surgery is the most effective weight loss therapy, its skeletal consequences are unclear. The aim of this study was to assess the impact of weight loss, gut hormones, adiponectin on bone loss in people undergoing Dieting (Diet), Gastric Banding (GB) and Gastric Sleeve (GS) over 24 months post-intervention.There were 15 Diet, 8 GB and 20 GS subjects with mean (±S.D.) age 53 (12) years and BMI 39 (6). At 12 months mea...