Endocrine Abstracts

Background: The use of high dose Ergot derived dopamine agonists in patients with Parkinson’s disease has been associated with an increased risk of cardiac valvular fibrosis. The UK Medicines and Health products Regulatory Agency (MHRA) currently advises baseline Echocardiogram within 3–6 months and follow up Echocardiogram at 6–12 monthly intervals in all patients taking ergot derived dopamine agonists. However, the risk of cardiac valvulopathy with lower doses...

We report an unusual case of struma ovarii diagnosed after thyroidectomy for Graves’ disease and papillary thyroid cancer.A 46-year-old woman presented with a 3-month history of weight loss, palpitations and irregular periods. Physical examination revealed tachycardia, fine tremor and a diffuse goitre. TSH <0.1 (0.5–4.2 mU/l), FreeT4 26 (10.8–19.3 pmol/l) confirmed thyrotoxicosis.Thyroid ultrasound scan showed a ...

PCOS affects ~10% of women of reproductive age and is characterised by hyperandrogenism and ovulatory dysfunction. About 60% of women with PCOS are overweight, with an increased risk of developing type 2 diabetes mellitus.This Local Ethics Committee approved study aimed to determine the optimum composition of a weight reducing diet in management of women with PCOS. It compared the effect of a low carbohydrate with that of a low glycaemic index (GI) diet ...

Objective: PCOS affects approximately 10% of women of reproductive age. An audit of our PCOS clinic showed that 75% of our patients were overweight or obese. Following this a Nurse led PCOS weight management clinic was developed. The aim of this audit was to determine whether the Nurse led clinic was effective in helping overweight women with PCOS lose weight.Methods: Data was collected on women attending the clinic at each monthly appointment since Apri...

Parathyroid carcinoma accounts for 0.5–5% of primary hyperparathyroidism. Preoperative diagnosis is difficult.A 33-year-old butcher presented in July 2007 with a 3 month history of nausea, abdominal pain, loss of appetite, general weakness and 1 stone weight loss. He denied polyuria, polydipsia or bone pain.Past history included Raynaud’s disease, depression and panic attacks. His regular medications were omeprazole and p...

Objective: The aim of our audit was to determine the effectiveness of first dose Radioiodine (RAI) in curing thyrotoxicosis, comparing our results with published rates of success and hypothyroidism.Methods: All patients with thyrotoxicosis treated with RAI between 2002 – 2004 (n=71) were identified and casenotes reviewed. Patients were either given nominal doses of either 259 or 407 MBq. Data collected included: the cause of thyrotoxicosis, g...

Background: The Glucagon-like peptide-1 receptor agonist (GLP1RA) semaglutide has shown improvements in glycaemia and other metabolic parameters for patients with type 2 diabetes (T2D) in clinical trials. Published real-world data are sparse and there are none from the Middle East where semaglutide became available in 2020.Method and Results: We retrospectively gathered data for 289 patients (median age 50 years (IQR 42-57), 36% female, 87% Emirati and 8...