Searchable abstracts of presentations at key conferences in endocrinology

ea0063mte10 | (1) | ECE2019

NCAH and Female Reproduction

Ertorer Melek Eda

Nonclassical Congenital Adrenal Hyperplasia (NCAH) usually due to 21 Hydroxylase deficiency (21OHD) is an autosomal recessive disease, occurring in upto 1/200 of Caucasians and more often in certain ethnic groups. Common CYP21A2 mutations from most severe to mildest are; null, I2 splice, I172N, P30L, and V281L. Mutations leaving 20–70% of enzyme activity is responsible for NCAH, mostly caused by V281L mutation. About 25–50% of patients are homozygous or compound hete...

ea0049ep969 | Pituitary - Clinical | ECE2017

A case with headache and pitosis: pituitary macroadenoma or ophtalmoplegic migraine?

Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Bakiner Okan , Bozkirli Emre , Ertorer Melek Eda

Case: A 28-year old man was admitted to our hospital with complaints of three days of severe headache, diplopia and ptosis of the right eye. He had pituitary macroadenoma and had been on cabergolin 0.25 mg/week for the last six months. At physical examination, he demonstrated ptosis and inability to move the right eye medially. Magnetic resonance imaging showed a 13×12 mm pituitary mass with suprasellar extension and hemorrhage. Visual field analysis was abnormal except t...

ea0041ep291 | Clinical case reports - Pituitary/Adrenal | ECE2016

Radiotherapy for nasopharyngeal carcinoma: a rare cause of hypopituitarism

Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Bozkirli Emre , Bakiner Okan , Ertorer Melek Eda

Introduction: Radiotherapy to the head and neck area is the standard therapy used for the treatment of nasopharyngeal carcinoma. Hypopituitarism is a well-known late complication of cranial radiotherapy. Although very rarely, it may be observed following radiotherapy to the head and neck area, as well.Case report: A 53-year-old man was referred to our endocrinology department for hyponatremia and low free thyroxine (T4) with normal thyroid- st...

ea0022p155 | Cardiovascular endocrinology and lipid metabolism | ECE2010

Increased plasma viscosity is a predictor of high cardiovascular risk in women with PCOS

Haydardedeoglu Filiz Eksi , Ertorer Melek Eda , Haydardedeoglu Bulent , Kozanoglu Ilknur , Anaforoglu Inan , Tutuncu Neslihan Bascil

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrinopathy that affects 5–10% of women of reproductive age. It is now recognized as not only a reproductive but also a metabolic disorder with co-morbidities, such as; diabetes, dyslipidemia, hypertension, etc. All these metabolic abnormalities predispose women with PCOS to atherosclerosis. Plasma viscosity is a major determinant of blood flow in microcirculation. Preliminary data indicate that elevated plasma...

ea0056p371 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

A difficult synchronous diagnosis; Type 2 Diabetes and insulinoma

Sefa Bakiner Okan , Bozkirli Emre , Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Ertorer Melek Eda

Background: In the literature there are rare cases of patients with known Type 2 Diabetes Mellitus whom are diagnosed as insulinoma. However a synchronous diagnosis with insulinoma and diabetes for a patient presenting with hypoglycemia symptoms is not an expected condition.Case: A 79 years-old female patient was sent to our Endocrinology outpatient clinic because of repeating minor and major hypoglycemia attacks. She had no important finding in her back...

ea0056p372 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Immunoglobulin G4 related pancreatitis; can it be a rare cause of secondary diabetes?

Bozkirli Emre , Bakiner Okan Sefa , Bagir Gulay Simsek , Haydardedeoglu Filiz Eksi , Ertorer Melek Eda

Background: Autoimmune pancreatitis (AIP) is a relatively new entity in which the exocrine pancreas shows lymphocytic infiltration. There are two subtypes of AIP; Type 1 related with Immunoglobulin G4 (IgG4) as the pancreatic manifestation of IgG4-related disease (IgG4-RD), and Type 2 related with granulocytic infiltration. The characteristic features of Type 1 AIP are increased serum IgG4 levels, lymphoplasmacytic sclerosing pancreatitis (infiltration of IgG4+ plasmacytes and...

ea0056p697 | Clinical case reports - Pituitary/Adrenal | ECE2018

Pasireotide a new option for acromegaly

Haydardedeoglu Filiz Eksi , Bakiner Okan , Bozkirli Emre , Bagir Gulay Simsek , Ertorer Melek Eda

Background: Acromegaly is a rare neuroendocrine disorder caused by secretion of excessive levels of growth hormone. Somatostatin receptor ligands (SRLs) are first-line medical therapies for patients in whom surgery has failed or is contraindicated. We report a case who had inadequate response to multiple therapies including surgery,radiotherapy,octreotide,lanreotide,cabergoline and pegvisomant.Case: An 44-year-old woman was admitted to our hospital with ...

ea0056p1129 | Thyroid cancer | ECE2018

Hounsfield unit value has null effect on thyroid nodules at 18F-FDG PET/CT scans

Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Torun Nese , Kocer Nazim Emrah , Reyhan Mehmet , Ertorer Melek Eda

Objectives: Detection rate of thyroid nodules is increasing with use of new imaging modalities, like 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT). To avoid unnecessary operations, differentiating between benign and malignant 18F-FDG PET/CT-positive thyroid nodules is essential. Many authorities recommend fine needle aspiration biopsy (FNAB) for exclusion of malignancy in thyroid nodules. Although FNAB is a simple, easily performed proc...

ea0056ep44 | Diabetes, Obesity and Metabolism | ECE2018

Are plasmathyrotropin levels associated with degree of obesity and metabolic syndrome in euthyroid obese patients?

Bakiner Okan Sefa , Bozkirli Emre , Cavlak Gulhan , Ozsahin Kursad , Ertorer Melek Eda

We aimed to observe the association between degree of obesity and metabolic syndrome and plasma thyrotropin levels in obese, euthyroid patients. 947 obese and overweight patients who admitted to our outpatient clinic were assessed retrospectively. 150 healthy euthyroid cases were also recruited as the control group. Cases with metabolic syndrome were determined. Patients were divided into various subgroups as overweight, obese, morbid obese, men, and women. No statistical sign...

ea0090rc3.5 | Rapid Communications 3: Pituitary and Neuroendocrinology 1 | ECE2023

The Reassessment of Therapeutic Decisions by Clinicians According to the SAGIT® Instrument in Acromegaly: Results of a Multicenter Study

Turgut Seda , Ciftci Sema , Yilmaz Nusret , Uysal Serhat , Muradov İlkin , Kılıc Kan Elif , Cansu Guven Baris , Yenidunya Yalın Gulşah , Uc Ziynet ALphan , Sarıbeyliler Goktuğ , Pehlivan Esma , Bagir Gulay Simsek , Tanrikulu Seher , Yaylali Guzin , Mısıroğlu Fuat , Omma Tulay , Selcukbiricik Ozlem Soyluk , Cakir İlkay , Yurekli Banu Sarer , Ertorer Melek Eda , Kadioglu Pinar , Saygili Fusun , Yarman Sema

Objective: SAGIT, a new instrument designed for therapeutic decision, is not routinely used yet. While the medical treatment was mostly planned according to disease activity by hormonal evaluation, the therapeutic decision has tried to be standardized with the SAGIT instrument. The aim of this study is to reassess the therapeutic decisions by clinicians in the management of acromegaly according to the SAGIT instrument.Material and Method: This multicente...