Endocrine Abstracts

Background and aims: Comparative animal study of efficacy of intermittent short courses administration of lyophilized single-, three- and alive multistrain probiotic on insulin resistance in rats with experimental obesity.Methods: We included 70 rats divided into 7 groups (n=10 in each). Rats of group I were intact. Newborn rats of groups II-VII were injected with monosodium glutamate (MSG) (4 mg/g). Rats of group II (MSG-obesity group) were unt...

Introduction: The beneficial interaction between the microbiota and humans is the way how bacteria contained within the gut ‘talk’ to the immune system. Into this landscape probiotics and nutraceuticals play a major role. The study aims to determine whether probiotics plus nutraceuticals such as smectite or omega-3 are superior to probiotic alone on the monosodium glutamate (MSG) induced obesity model in rats.Methods: Totally 7...

Background: Probiotics and omega-3 polyunsaturated fatty acids supplementation (PUFA) have beneficial effect on obesity related disorders in animal models. We have previously shown, on rats with monosodium glutamate-induced obesity, that in take of the combination based on live probiotics and omega-3 PUFA is accompanied by the preventive effect concerning experimental obesity development, lead toinsulin resistance (IR) improvement and more obvious decrease of he paticsteatosis...

Background: Probiotics have beneficial effect on obesity/type 2 diabetes (T2D) related disorders in both animal models and clinical trials, at the same time, some scientific papers question the effectiveness and the safety of probiotics. In turn, postbiotics are preparations of inanimate microorganisms and / or their components, which are directly identified with the safety of their use and the health benefits of the host.Aim: To conduct placebo-controll...

Background: Post-COVID-19 condition (long COVID-19, post-acute COVID-19, long-term effects of COVID-19) is an emerging health problem in people recovering from COVID-19 infection within the past 4-6 months. Patients with type 2 diabetes (T2D) are in the risk group for a more severe course of COVID-19 and the development of its complications. Aim: to define the prevalence and prediction of post-COVID-syndrome development in patients with T2D according to ...