Endocrine Abstracts

Glucose uptake is mediated by a family of glucose transport proteins, which are known to be expressed in specific insulin-sensitive tissues. Magnesium (Mg) is essential for autophosrylation of insulin receptor (INSR) and translocation of glucose transporter 4 (GLUT4) to the plasma membrane to facilitate glucose homeostasis. The specific effect of magnesium on INSR and GLUT4 expression in a diabetic state is however lacking. We conducted this s...

Glucose uptake is mediated by a family of glucose transport proteins, which are known to be expressed in specific insulin-sensitive tissues. Magnesium (Mg) is essential for autophosrylation of insulin receptor (INSR) and translocation of glucose transporter 4 (GLUT4) to the plasma membrane to facilitate glucose homeostasis. The specific effect of magnesium on INSR and GLUT4 expression in a diabetic state is however lacking. We conducted this s...

Maternal obesity is associated with altered metabolic function in the offspring, but its age and sex-specific metabolic effect not clearly defined. Female adult Sprague–Dawley (SD) rats were fed an obesogenic diet – high fat diet of 7.76 kcal/g (experimental group) or standard rat chow (3.52 kcal/g, control group) for 8 weeks prior to mating and throughout gestation and lactation. Proven fertile male SD rats were used for mating. Male and female offspring were weaned...

The female reproductive system provides several functions. These include ovulation, pregnancy and childbirth. The incidence of diabetes mellitus (DM) is increasing rapidly worldwide and it is associated with reproductive complications. Metformin is an oral hypoglycaemic drug used in the management of DM. The present study determined the effect of metformin on some reproductive function in alloxan-induced diabetic female Sprague-Dawley rats.<p class="abst...

The female reproductive system provides several functions. These include ovulation, pregnancy and childbirth. The incidence of diabetes mellitus (DM) is increasing rapidly worldwide and it is associated with reproductive complications. Metformin is an oral hypoglycaemic drug used in the management of DM. The present study determined the effect of metformin on some reproductive function in alloxan-induced diabetic female Sprague-Dawley rats.<p class="abst...