Searchable abstracts of presentations at key conferences in endocrinology

ea0086p240 | Neuroendocrinology and Pituitary | SFEBES2022

UK practice on incidental (presumed) non-functioning pituitary microadenomas: a 13-year interval comparison

Hamblin Ross , Fountas Athanasios , Levy Miles J , Karavitaki Niki

Introduction: The optimal management approach for incidental non-functioning pituitary microadenomas (micro-NFAs) is unclear. We aimed to capture current UK practice and identify changes following a 13-year interval.Methods: Two surveys on micro-NFAs were conducted in 2009 and 2022 (advertised by Society for Endocrinology). Hormonal/imaging evaluations were explored.Results: 2022: 150 clinicians participated. At baseline, ≥14...

ea0090p404 | Pituitary and Neuroendocrinology | ECE2023

Prevalence of transient and permanent diabetes insipidus after transsphenoidal pituitary surgery: A systematic review and meta-analysis

Fountas Athanasios , Coulden Amy , Allotey John , Karavitaki Niki

Introduction: Patients undergoing transsphenoidal pituitary surgery (TPS) may develop water balance disorders post-operatively, with diabetes insipidus (DI) being the most common. Nonetheless, data on the prevalence of post-operative DI are not consistent necessitating a systematic review of the literature.Aim: To estimate the prevalence of DI following TPS in patients with pituitary adenomas (PAs), craniopharyngiomas and Rathke’s cleft cysts (RCCs)...

ea0077p86 | Neuroendocrinology and Pituitary | SFEBES2021

A rare case of sellar pathology: Coinciding IgG4-related hypophysitis and pituitary adenoma

Hakami Osamah , Fountas Athanasios , Chavda Swarupsinh , Tsermoulas George , Ayuk John , Batra Ruchika , Karavitaki Niki

A 69-year-old man was referred to our Pituitary Service for a 3-month history of progressive right visual loss and a finding of “pituitary enlargement” on brain MRI. He reported erectile dysfunction and his medical history included asthma, DM2 and meningitis (8 years ago). Neuro-ophthalmology review showed visual acuity 6/60, optic neuropathy, marked visual field loss with residual superonasal island in right eye, mild 6th nerve palsy. Pituitary MRI: infil...

ea0059p128 | Neuroendocrinology and pituitary | SFEBES2018

Are silent corticotroph adenomas high risk tumours for recurrence? Systematic review and meta-analysis

Fountas Athanasios , Lavrentaki Aikaterini , Subramanian Anuradhaa , Toulis Konstantinos , Nirantharakumar Krishnarajah , Karavitaki Niki

Introduction: The 2017 WHO Classification of Pituitary Tumors grades silent corticotroph adenomas (SCAs) as high-risk adenomas due to their aggressive clinical behaviour (high probability of recurrence). Nonetheless, studies comparing recurrence rates of SCA with other non-functioning pituitary adenomas (NFPAs) subtypes have provided conflicting results necessitating review of the evidence this recommendation relies on.Aims: To estimate recurrence rates ...

ea0099ep573 | Thyroid | ECE2024

Asymptomatic subacute thyroiditis presenting as bilateral thyroid nodules and pyrexia of unknown origin

Kaliakatsou Eirini , Fountas Athanasios , Papanastasiou Labrini , Pikou Vasiliki , Koutete Dimitra , Mpaltas Christos , Markou Athina

Introduction: Subacute thyroiditis (SAT) is an acute inflammatory disorder which can rarely present as pyrexia of unknown origin without other symptoms. Diffuse thyroid heterogeneity, focal hypoechoic areas and decreased/normal gland vascularity are the most common ultrasound findings of SAT. We report a case of asymptomatic SAT presenting as bilateral thyroid nodules and pyrexia of unknown origin.Case Presentation: A 72-year-old male with a history of t...

ea0081p522 | Adrenal and Cardiovascular Endocrinology | ECE2022

Gastric monomorphic epitheliotropic intestinal T-cell lymphoma with bilateral adrenal metastases

Kaliakatsou Eirini , Markou Athina , Papanastasiou Labrini , Giagourta Irini , Kalantzi Athanasia , Dimitriadi Anastasia , Lenos Michael , Kounadi Theodora , Fountas Athanasios

Introduction: Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL), formerly known as type II enteropathy-associated T-cell lymphoma, is a rare and aggressive subtype of lymphoma of the gastrointestinal track typically noted in Asian or Hispanic populations. Adrenal involvement as part of MEITL is extremely rare. Herein we present a patient of Greek origin with MEITL and bilateral adrenal metastases.Case Presentation: A 74-year-old man presente...

ea0059p138 | Neuroendocrinology and pituitary | SFEBES2018

Outcomes of bilateral adrenalectomy in ACTH-dependent Cushing’s syndrome

Samani Niraj , Fountas Athanasios , Chai Shu Teng , Gleeson Helena , Ayuk John , Arlt Wiebke , Toogood Andy , Gittoes Neil , Karavitaki Niki

Introduction: Bilateral adrenalectomy (BADx) is a treatment option in ACTH-dependent Cushing’s syndrome refractory to other therapeutic modalities or can be an emergency measure in cases with severe manifestations of hypercortisolaemia.Aim: To review the outcomes of our patients with ACTH-dependent Cushing’s offered BADx.Methods: Records of patients with ACTH-dependent Cushing’s managed by BADx and seen in our Depart...

ea0099p18 | Adrenal and Cardiovascular Endocrinology | ECE2024

Clinical, biochemical, histopathological, and metabolic characteristics of patients with pheochromocytomas

Kakargia Eleftheria , Fountas Athanasios , Markou Athina , Giagourta IRINI , Zerva Dimitra , Choreftaki Theodosia , Zografos Giorgos , Aggeli Chrysanthi , Papanastasiou Labrini

Introduction: Pheocromocytomas represent a rare clinical entity with an incidence of approximately 0.8 per 100 000 person-years. Due to their rarity, the characteristics of patients with pheochromocytoma have not been thoroughly investigated yet.Aim: The assessment of pre- and post-operative clinical and biochemical characteristics as well as the evaluation of imaging and histological data of patients with pheochromocytomas.Design:...

ea0099p325 | Pituitary and Neuroendocrinology | ECE2024

Cyclic cushing’s syndrome: a diagnostic challenge

Tsironi Ioanna , Papanastasiou Labrini , Fountas Athanasios , Kaliakatsou Eirini , Karachalios Kostis , Christou Panagiota , Tigas Stelios , Gravvanis Miltiadis , Markou Athina

Introduction: Cyclic Cushing’s syndrome is a rare disease characterized by episodes of cortisol hypersecretion followed by periods of normal cortisol secretion, ranging from days to months. We report a case of cyclic Cushing’s syndrome whose diagnosis was delayed for years.Case presentation: A 50-year-old female with a 16-year history of non-Hodgkin’s lymphoma was referred to the Endocrinology Unit due to suspected hypercortisolemia. She h...

ea0099p157 | Thyroid | ECE2024

Plasmablastic lymphoma presenting as a rapidly increasing thyroid mass: a case report

Paschalidi Charikleia , Fountas Athanasios , Markou Athina , Vlachou Charikleia , Efthymia Bazani , Gorgolidis Georgios , Sassi Marina , Nitsios Ioannis , Liokati Ioanna , Papastergiou George , Papanastasiou Labrini

Introduction: Primary thyroid lymphoma is a rare entity accounting for <5% of thyroid malignancies and <2% of extra-nodal lymphomas with diffuse large B-cell lymphoma (DLBCL) being the most common subtype. Plasmablastic lymphoma (PBL) is an uncommon and aggressive subtype of DLBCL mainly detected in patients with immunosuppression, especially related to HIV infection. Typically, PBL occurs in extra-nodal sites, usually the oral cavity and the gastrointestinal tract whi...