Endocrine Abstracts

Introduction: Osteoporosis is a well known long-term complication after simultaneous pancreas kidney transplantation (SPK). Alterations of bone microstructure contribute to the risk of fracture and trabecular bone score (TBS) measurement offers and additional tool to quantify bone microarchitecture impairment.Methods: There were 33 subjects with type 1 diabetes mellitus (23 men, 10 women, mean age 43.4 ± 9.8 years) participating in a prospective obs...

Introduction: Metabolic syndrome (MetS), the combination of obesity, glucose metabolism impairment, dyslipidemia and high blood pressure, is becoming a worldwide burden of morbidity and mortality. Both genetic and enviromental factors are involved in its pathogenesis, with heritability of each component of MetS 25–80%.Aim: We aim to contribute to dissection of the genetic architecture of MetS using PD (polydactylous) rats, which present a unique mi...