Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep1206 | Late Breaking | ECE2022

The impact of gh treatment in turner syndrome

Hrisca Anamaria , Dumitru Teodora , Andrei Diana , Florescu Alexandru , Leustean Letitia , Rusu Cristina , Preda Cristina , Ungureanu Maria Christina

Introduction: The treatment with growth hormone (GH) plays an essential role in the Turner syndrome (TS) management. This study evaluated its efficacy in improving adult height (AH) and metabolic parameters.Material and methods: We retrospectively analysed auxological, biochemical, genetic and pharmacological parameters of 56 girls with confirmed TS. They were categorised according to their karyotype as X monosomy (62%), isochromosome (17%), X mosaicism ...

ea0063ep105 | Pituitary and Neuroendocrinology | ECE2019

Therapeutic challenges in a case of TSH/GH co-secreting pituitary macroadenoma

Hrisca Anamaria , Balineanu Ginuta , Tudurean-Olteanu Georgiana , Nechita Mirela , Potorac Iulia , Leustean Letitia , Preda Cristina , Ungureanu Maria Christina

Introduction: Thyrotropin-secreting pituitary adenomas are rare tumors accounting for 1–2% of all pituitary adenomas and the diagnosis is based on the combination of high fT4 levels with normal to high TSH concentration in the presence of a pituitary adenoma. About one third co-secrete other hormones, of which, most frequently growth hormone (16%) followed by prolactin and gonadotropins.Case report: A 60 years-old male patient presented in 2016 afte...

ea0056p149 | Neuroendocrinology | ECE2018

Diagnostic difficulties, management and treatment in neuroendocrine tumors

Nechita Mirela Claudia , Tudurean-Olteanu Anca Georgiana , Hrisca Anamaria , Stefanescu Cipriana , Stolniceanu Cati Raluca , Florescu Alexandru , Ungureanu Maria Christina

Introduction: Diagnosis of NETs (neuroendocrine tumors) is based on clinical manifestations, peptide and amine secretion, specialized radiological and nuclear imaging, secured by detailed histology and immunohistochemistry, which should be obtained whenever possible. Biomarkers are still the mainstay in the diagnosis and follow-up of patients with NETs.Case report: We present the case of a 36-year-old patient with no significant pathological personal his...

ea0056p708 | Clinical case reports - Pituitary/Adrenal | ECE2018

Bromocriptine for management of a patient with cranipharyngioma and central hyperthermia after neurosurgery: a case report

Tudurean-Olteanu Anca-Georgiana , Hrisca Anamaria , Nechita Mirela Claudia , Rotariu Daniel , Preda Cristina , Leustean Letitia , Ungureanu Maria Christina

Introduction: Central hyperthermia is frequent in patients with brain injury and is characterized by a rapid onset with high temperatures, marked temperature fluctuations and poor response to antipyretics. It is associated with worse outcomes in the injured brain, thus it is important to aggressively manage it.Case-report: We report a case of a 9-year-old boy diagnosed with sellar and suprasellar adamantimomatous craniopharyngioma at the age of 5 when he...

ea0056p1000 | Clinical case reports - Thyroid/Others | ECE2018

Thyroid hormone resistance and pituitary macroadenoma: is there a connection? – case report

Hrisca Anamaria , Tudurean Olteanu Georgiana , Nechita Mirela , Bilha Stefana , Rotariu Daniel , Leustean Letitia , Preda Cristina , Christina Ungureanu Maria

Introduction: Inappropriate secretion of TSH, despite elevated levels of T4, is due to either a TSH-secreting adenoma (TSHoma) or thyroid hormone resistance (RTH). RTH is a rare disorder, usually caused by mutations in the thyroid hormone receptor beta, characterized by a variable tissue hyporesponsiveness to thyroid hormone. The increased level of TSH may predispose to thyrotroph hyperplasia and possible adenoma formation.Case report: A 21 years old fem...

ea0056p96 | Clinical case reports - Pituitary/Adrenal | ECE2018

From gastric sleeve to diagnosis of a rare familial multiple endocrine neoplasia type 1

Tudurean-Olteanu Anca Georgiana , Danila Radu , Nechita Mirela Claudia , Dumitrascu Andreea-Nicoleta , Preda Cristina , Leustean Letitia , Hrisca Anamaria , Ungureanu Maria Christina

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is an autosomal-dominant hereditary disorder characterized by the presence of two of the three main endocrine tumors that are parathyroid, pituitary adenomas and enteropancreatic tumors.Case-report: We report a case of a 71-year-old obese patient with repeated unsuccessful attempts to weight loss who was admitted to the surgical department for the bariatric treatment of obesity (BMI=48,22 kg/m...