Endocrine Abstracts

The transition of hypothyroidism from Hashimoto’s thyroiditis into hyperthyroidism (Graves’ disease) is uncommon, and the underlying causes are still unknown. We studied clinical characteristics in patients with the conversion of preexisting Hashimoto’s thyroiditis to Graves’ disease compared to patients with Hashimoto’s thyroiditis or Graves’ disease alone.Patients and Methods: Retrospective comparative case series of 42 pa...

Introduction: Some new data suggest a coincidence of differentiated thyroid carcinoma in patients with primary hyperparathyroidism (pHPT).Methods & design: We performed a retrospective analysis of our patients (n=267) with primary hyperparathyroidism from 2007 until 2011.Results: Musculoskeletal pain was reported by 34.2% of the patients. Gastrointestinal discomfort was complained by 28.8%, and 21.1% had nephrolithiasi...

Subject: Use of intraoperative ultrasound (iUS) during transshenoidal surgery addresses (a) resection control of macroadenomas and (b) identification of microadenomas, thus avoiding extensive pituitary exploration.Method: (a) For resection control of 33 pituitary macroadenomas and 2 meningeomas a 13 MHz US probe with a perpendicular 10 mm linear field was introduced into the sella after intrasellar resection to investigate the suprasellar and parasellar ...

Immortalized human thyroid follicular epithelial cell lines represent a valuable tool for the investigation of thyroid physiology in vitro. While there is an extensive selection of human thyroid carcinoma cell lines, the number of healthy follicular epithelial cell lines is limited. The vast majority of studies on thyroid physiology is based on the human immortalized cell line Nthy-ori 3-1, leading to comprehensive characterization of this cell line. However, in 2021 ...