Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep903 | Thyroid cancer | ECE2015

Familial non-medullary thyroid cancers tend to be more bilateral and have more capsular invasion compared to non-familial ones

Yazici Dilek , Kapran Yersu , Demirkol Onur , Terzioglu Tarik , Tezelman Serdar , Alagol Faruk

Introduction: Currently, about 5–15% of non-medullary thyroid cancers (FNMTC) are considered to be of familial origin. These are either syndrome-associated tumours or non-syndromic tumours. The aim of the study was to determine the clinical, pathological and biochemical characteristics of FNMTC compared to non-familial ones with a follow-up of 10 years.Methods: Among FNMCT followed by a single physician, 62 patients with papillary cancer were screen...

ea0035p593 | Endocrine tumours and neoplasia | ECE2014

IGF1 gene polymorphism and thyroid cancer

Soyluk Ozlem , Aral Ferihan , Boztepe Harika , Kapran Yersu , Erbil Yesim , Ustek Duran , Abaci Neslihan , Colak Nese

Aim: Several studies suggested that there is a relationship between serum levels of IGF1 or their polymorhisms and some cancer types. The genetic polymorphism in the region of IGF promoter region which is composed of cytosine–adenine repeats, affects the promoter activity. It is suggested that serum IGF1 levels are inversely associated with the length of CA repeats. There are studies reporting that the carriers of the CA 19 allele are more likely to develop some cancer ty...

ea0020p176 | Endocrine tumours and neoplasia | ECE2009

Ectopic growth hormone-releasing hormone secretion by a neuroendocrine tumor causing acromegaly: long-term follow-up results

Ozbey Nese Colak , Kapran Yersu , Bozbora Alp , Erbil Yesim , Tascioglu Cemil , Asa Silvia L

Less than 1% cases of acromegaly is caused by ectopic secretion of growth hormone releasing hormone (GHRH).A 25-year-old woman was admitted to the hospital, with iron deficiency anemia, acromegaly and a 6×6 cm mass in infrahepatic location near to the pancreatic head. Sellar magnetic resonance (MR) imaging indicated pituitary enlargement without obvious evidence of a pituitary adenoma. The patients underwent abdominal exploration. Histopathological ...

ea0014p361 | (1) | ECE2007

ret/PTC oncogene expression in papillary thyroid carcinoma

Arpaci Dilek , Kapran Yersu , Uzum Ayse Kubat , Aral Ferihan , Ozbey Nese , Alagol Faruk

Objective: We aimed to investigate the expression of ret/PTC oncogene in PTC and to determine the relationship of this expression with clinical parameters and the prognosis.Materials and methods: Surgical specimens of 45 PTC and adjacent normal thyroid tissues were obtained from the files of the Department of Pathology at Istanbul Faculty of Medicine, Istanbul University. All of the patients had definite diagnosis of PTC between 1995–2003 and had ad...