ea0073aep554 | Pituitary and Neuroendocrinology | ECE2021
Kim Kang Min
, Go Seon Myeong
, Jeong Sunhwa
, Lee Jimin
, Jeung Eui Bae
Ki-67 can be solely detected within the cell nucleus, whereas in mitosis, most of the Ki-67 proteins are located on the chromosome surface. Ki-67 is present during all phases of the cell cycle (G1, S, G2, and M), but BrdU is only present in the S phase. This study examined whether it is possible to establish a developmental neurotoxicity test in human neural progenitor cells using Ki-67 instead of BrdU (5-bromo-2-deoxyuridine). In the present study, Ki-67-expressed ReNce...