Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp193 | Pituitary & endocrine Tumours | ECE2017

Amenorrhea without vasomotor symptoms in women over 40: A sign of pathological hyperprolactinemia?

Ilovayskaya Irena , Dreval Alexader , Krivosheeva Yulia

Background: Hyperprolactinemia is often seen in women of reproductive age (20–35 years), most often due to microprolactinoma. However, prolactinomas do occur in older women.Objective: To analyze clinical features of hyperprolactinemia in women >40 yearsMaterial and methods: Clinical and biochemical data of 185 women with pathological hyperprolactinemia were analyzed.Results: Seventy (37.8%) patients ...

ea0090ep777 | Pituitary and Neuroendocrinology | ECE2023

Differential diagnosis of the progressing pituitary lesion in a pregnant woman

Ilovayskaya Irena , Mikhaylova Daria , Krivosheeva Yulia , Komerdus Irina

A 31-year-old female patient without previous history of pituitary diseases, at 16 weeks of 4th spontaneous pregnancy complained about severe headache; diplopia and right ptosis developed shortly, nausea and vomiting appeared. Brain MRI showed the mass lesion 30×19×14 mm (frontal×vertical×sagittal) with supra-laterosellar extension, deforming and displacing optic chiasm; signs of pansinusitis, pathological contents of the right mastoid cells, vascular malfo...

ea0041ep918 | Pituitary - Clinical | ECE2016

Clinical proofs for necessity of macroprolactinemia screening

Ilovayskaya Irena , Dreval Alexander , Krivosheeva Yulia , Osipova Tatiana

Prevalence of macroprolactin in serum (>40%) can be a cause of asymptomatic hyperprolactinemia. However, there is still lack of evidence how to manage with symptomatic patients with macroprolactinemia.We analyzed clinical data and monomeric prolactin levels in 85 women of reproductive age with hyperprolactinemia: NonTumor hyperprolactinemia (NT, n=31), MIcroadenomas (MI, n=32), MAcroadenomas (MA, n=22). Prolactin levels 171...

ea0041ep922 | Pituitary - Clinical | ECE2016

Clinical characteristics of giant pituitary adenomas

Ilovayskaya Irena , Dreval Alexander , Krivosheeva Yulia , Stashuk Galina

Our Pituitary Tumour Registry includes data about 346 patients with pituitary macroadenomas: 142 non-functional adenomas (NFA) including 18 (12.7%) giant, 62 macroprolactinomas – 6 (9.7%) giant, 141 somatotropinomas – 6 (4.3%) giant. We analysed clinical features of these 30 giant pituitary tumors (<40 mm at least one of the sizes): 18 NFA (11 Females; 7 Males), 6 prolactinomas (3 Females; 3 Males), 6 somatotropinomas (3 Females; 3 Males). Patients with giant NFA...

ea0037ep790 | Pituitary: clinical | ECE2015

Prevalence of the sleep breathing disorders in untreated and treated patients with acromegaly

Ilovayskaya Irena , Dreval Alexander , Krivosheeva Yulia , Abramenko Alexander , Stashuk Galina

There are some data concerning high prevalence of infrasellar extension of somatotropinomas. To reveal any differences expansion of pitutary macroadenomas with various hormonal secretion, we have analyzed MRI data of 175 pituitary macroadenomas: 87 non-functioning adenomas (NFAs), 48 prolactinomas, 43 somatotropinomas. The sizes of pituitary tumour (vertical, sagittal, frontal): NFAs 24 (17.5; 34.5)mm, 23 (17.4; 28) mm, 23 (18; 30) mm; prolactinomas 21 (15; 31) mm, 20 (16; 30)...

ea0037ep820 | Pituitary: clinical | ECE2015

High BMI in female patients with prolactinomas

Ilovayskaya Irena , Dreval Alexander , Krivosheeva Yulia , Chikh Irina , Stashuk Galina

We analysed BMI of 270 female patients: 148 with hyperprolactinaemia (non-tumoural hyperprolactinaemia, n=46; microadenomas, n=56; and macroadenomas, n=46), 55 with isolated central hypogonadism, 67 with hypopituitarism. Additionally, 53 healthy women of reproductive age and 51 postmenopausal women were examined. In patients with hyperprolactinaemia median prolactin levels were 1547 (1124; 2185), 1490 (1050; 2280), and 3100 (1790; 18840) mE/l, accord...