Searchable abstracts of presentations at key conferences in endocrinology

ea0065sk1.3 | Being a consultant – How to get the job and keep it | SFEBES2019

How do I set up a new service?

Lansdown Andrew

Setting up a new service begins with identifying patient needs at both a local and national level, with the goal of producing higher quality and more sustainable services, improved health outcomes, reduced health inequalities and better models of care. Aims and objectives of the new service need to be clearly laid out early on, with the support and input from all stakeholders to ensure its wider acceptance and long-term success. Building a business c...

ea00100wc2.1 | Workshop C: Disorders of the thyroid gland | SFEEU2024

Radiofrequency ablation of toxic thyroid nodule

Muhammad Sadiqi Rana , Lansdown Andrew

Background: Radiofrequency ablation (RFA) is an outpatient image-guided thermal ablation procedure that is an alternative to surgery for treating thyroid nodules. It is minimally invasive, cosmetically superior and associated with less risk of hypothyroidism.Case: We discuss a case of 53 years old female who presented with palpitations, feeling hot, sweating, tremors, weight loss, and pins and needles. On examination, thyroid was palpable and there were ...

ea0090p553 | Adrenal and Cardiovascular Endocrinology | ECE2023

Cushingoid features in a patient with adrenal insufficiency secondary to combined inhaled steroid and Itraconazole therapy

Nagarajah Kalyani , George Lindsay , Lansdown Andrew

Background: Iatrogenic adrenal insufficiency (AI) refers to primary, secondary, or tertiary hypoadrenalism associated with drug administration, surgery, or irradiation. The most common cause of secondary adrenal insufficiency is exogenous glucocorticoids. Hepatic metabolism of inhaled corticosteroids (ICS) takes place via cytochrome P450 3A4. Nevertheless, it can be decreased by enzyme inhibitors such as itraconazole or ritonavir, thus leading to an increase in the bioavailabi...

ea0062p17 | Poster Presentations | EU2019

Self-diagnosis of De la Chapelle syndrome

Ahmad Sajjad , Ravindran Ravikumar , Lansdown Andrew

Case history: A 30 years old male Caucasian had his saliva tested on a self-funded commercial DNA testing to identify his ancestral roots. The markers for Y chromosome were found to be absent and further evaluation revealed him to have 46 XX karyotype.This was consistent with the diagnosis of De la Chapelle syndrome or XX male syndrome. Fluorescence in situ hybridization (FISH) studies confirmed the presence of SRY (sex determining region Y) gene which was responsible...

ea0086oc4.1 | Adrenal and Cardiovascular | SFEBES2022

Introducing technology to improve patient safety in adrenal insufficiency: a proof-of-concept delivery of a new smartphone app in steroid-dependent patients

Panagiotou Grigorios , Lewis Janet , Sall Seetal , Lansdown Andrew

Introduction: Although significant developments have been achieved in the management of steroid-dependent patients, little progress has been made in ensuring their safety using smartphone technology. We present the use of a novel app in steroid-dependent patients.Methods: A group of unselected individuals currently on steroid replacement due to adrenal insufficiency (AI) were assessed regarding their access to intramuscular (IM) hydrocortisone. A smartph...

ea0090p499 | Thyroid | ECE2023

Radioiodine therapy outcomes in benign thyroid disease at the University Hospital of Wales, UK

Nagarajah Kalyani , Jones Elizabeth , Witczak Justyna , Taylor Peter , Lansdown Andrew

Background: Radioiodine therapy (I-131) is commonly prescribed for benign thyroid disease in keeping with recommended guidelines.Aims: To determine the effectiveness of I-131 in treating benign thyroid disease and the rates of hypothyroidism following treatment and by diagnosis.Methods: We identified 100 patients who received radioiodine therapy between November 2013 and June 2015 from a database held in the Medical Physics Departm...

ea0090p528 | Thyroid | ECE2023

A case of Kikuchi-Fujimoto disease with fluctuating thyroid autoantibodies

Nagarajah Kalyani , Lei Yin Win , Lansdown Andrew , Witczak Justyna

Introduction: Kikuchi-Fujimoto disease (KFD) is a benign self-limiting disease presenting with fever and lymphadenitis and mostly affecting adults younger than 40 years of age and of Asian descent. Its aetiology and pathogenesis are unknown though KFD often occurs in patients with concomitant autoimmune illness such as autoimmune thyroiditis or lupus erythematosus (SLE). We report a case of a patient with KFD and fluctuating thyroid function and thyroid autoantibody levels.</p...

ea0090ep710 | Pituitary and Neuroendocrinology | ECE2023

Serum prolactin levels and correlation to clinical diagnosis: a study of 259 patients with hyperprolactinaemia

Yin Win Lei , Evans Carol , Tennant Sarah , Lansdown Andrew

Introduction: Hyperprolactinaemia is a common finding in endocrine practice and can be due to a number of causes. The degree of elevation of prolactin levels may sometimes be helpful in distinguishing between underlying aetiology.Aim: To determine if hyperprolactinaemia is correlated with clinical diagnosis in a cohort of patients in the endocrine service at a tertiary centre.Methods: A biochemistry database held at University Hosp...

ea0065p336 | Nursing practice | SFEBES2019

Effectiveness of a nurse-led adrenal incidentaloma (AI) clinic at the University Hospital of Wales, Cardiff

Lewis Janet , Hamdan Khaliq , Scholz Anna , Lansdown Andrew

Background: In December 2017, a Nurse-Led AI clinic was introduced at University Hospital of Wales, Cardiff for the evaluation and follow-up of these patients. The clinic pathway was based upon the 2016 European Society for Endocrinology (ESE) guidelines on the management of adrenal incidentalomas.Aim: To evaluate the effectiveness of this new service and the cost-saving benefit.Methods: Electronic and paper-based patient records w...

ea0062p56 | Poster Presentations | EU2019

Paraganglioma of the seminal vesicle

Ravindran Ravikumar , Witczak Justyna , Lansdown Andrew , Premawardhana LDKE

Case history: A 49-year-old male with hypertension (on doxazosin, amlodipine and perindopril), obesity (BMI 40 kg/m2) and recent DVT (on warfarin) presented with a few months’ history of episodic headaches, palpitations, light-headedness and sweats accompanied by facial pallor, occurring around twice weekly without warning. Symptoms were often worse when upright. Spontaneous recovery followed. He did not have a family history of endocrine disease. Clinical exam...