Endocrine Abstracts

The study group consists of 159 cases of chronic autoimmune thyroiditis (CAT) (age =40.48±15.22 years; F/M=156/3) distributed in 3 groups after the morpho-functional criteria: CAT with goiter – 48.43% cases (F/M=77/0); atrophic CAT – 33.33% cases (F/M=52/1); asymptomatic CAT – 18.24% cases (F/M=27/2). The thyroid ultrasonography allowed the thyroid volume measurement and the evaluation of the parenchyma echogenicity. Most of the cases presented a moderate (...

Aim: To study the etiology and the treatment of the non endemic goiter, in our region.Material and methods: The study group consisted of 67 children (F/M: 48/19; age: 4–17 years old) with non endemic goiter admitted in our hospital during the period, 2003–2008. The diagnostic procedures were represented by: the clinical examination (including the anthropometric measures and pubertal stages after Tanner’s criteria), laboratory data (serum c...

Aim: To show the etiology of thyromegaly in our region to asses the rationale treatment and follow up.Material and methods: Between 2005 and 2010, we have studied the prevalence and etiologic profile of the children with thyromegaly admitted in the Endocrinology Department of our hospital. The working protocol included: weight and length birth, gestational age, auxological parameters and pubertal stages after Tanner’s criteria, morphogram, laborator...

Background: Short stature can be a sign of a wide variety of pathologic conditions or inherited disorders.Aim: To show the etiology of short stature in our region in order to asses the rationale treatment and genetic advice.Material and methods: Between January 2004 and December 2009, we have studied the prevalence and etiologic profile of the children admitted in the Endocrinology Department of Children’s Clinical Hospital Ti...

Background: In 2019, the International CAH Registry (I-CAH) performed a benchmarking exercise of acute adrenal insufficiency related adverse events including adrenal crises (AC) and sick day episodes (SDE).Methods: In 2022, I-CAH data on children aged <18 years at first visit with 21-hydroxylase deficiency CAH from 35 centres in 19 countries were analysed to examine the current occurrence of SDE and AC and compared t...

Aims: We studied the association of newborn screening (NBS) on early infancy outcomes in 21-hydroxylase deficiency (21OHD) congenital adrenal hyperplasia (CAH), using I-CAH registry data.Methods: From 2018-2023, data was available for 121 infants with 21OHD CAH (52 male) during the first 90 days of life from 26 centres in 15 countries. NBS was performed in 15 centres from 9 countries.Result...

Background and Aim: Previous research using data from the I-CAH registry showed wide variation between countries in the provision of glucocorticoid (GC) replacement in congenital adrenal hyperplasia (CAH). In this study, we aimed to establish the impact of different GC doses on height and weight in children and young people with CAH.Methods: Data from children with CAH recorded in the I-CAH registry since 2003 was collected, providing a cohort of 1522 pa...