Searchable abstracts of presentations at key conferences in endocrinology

ea0090p620 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Mutation in MT-TV gene – a novel etiology of mitochondrial diabetes?

Ornelas Mariana , Resende Eduarda , Gouveia Pedro , Maritza Pontes Santos Sa Elena , Maria Morna Ferreira Margarida

Mitochondrial diseases are rare conditions with a wide phenotypic range. The inability of dysfunctional mitochondria to produce sufficient ATP results in multi-organic defects dependent on high aerobic such as pancreas. The most common endocrine disease related to mitochondrial diseases is diabetes mellitus and it is thought to be secondary to insulin deficiency. A 26-year-old pregnant patient with 26 weeks gestational age was referred to an Endocrinology appointment ...

ea0090ep595 | Endocrine-related Cancer | ECE2023

Immune checkpoint inhibitors induced endocrinopathies: a possible indicator of improved survival

Ornelas Mariana , Borges-Canha Marta , Gouveia Pedro , Maria Morna Ferreira Margarida , Resende Eduarda , Santos Sa Elena Maritza Pontes , Silvestre Abreu Francisco

Background: Immune checkpoint inhibitors (ICI) are an innovative oncologic therapy used in several types of solid and hematological neoplasms. This treatment enables the antitumoral immune system response and results in significant improvement of clinical outcomes and survival rate. However, endocrine related adverse effects (ERAE) have been related, with thyroid and pituitary dysfunction being the most common endocrine diseases described. An association between the surge of e...