Endocrine Abstracts

Background: Many antipsychotics are obesogenic and contribute to significant weight gain with serious implications on patients’ physical and mental well-being. However, patients on antipsychotics are often excluded from unmodified lifestyle-intervention weight management programmes and trials.Objectives: To determine if weight loss is possible for antipsychotic-medicated obese patients when enrolled in an unmodified lifestyle-intervention weight man...

Introduction: It appears recently that the lack of physical activity might not be a factor for obesity but rather a consequence of perceptual-motor difficulties (D’Hondt et al. 2011). Perception and action are two intertwined processes: perception is a means to action and action is a means to perception. Not being able to perceive correctly visual or auditory information would alter someone’s movement kinematics of any given task. The key question is how do ...

Abstract: Obesity has reached epidemic proportions globally. At least 2.8 million people die each year as a result of being overweight or obese, the biggest burden being obesity-related diseases. Glucagon like peptide 1 (GLP-1) targeted therapies show the greatest potential for intervention and are approved as weight loss agents. However not all patients respond to GLP-1 therapy. Understanding the mechanisms of bodyweight regulation and their role in GLP-1 responders vs. non-r...

Introduction: Patients in secure forensic psychiatric units are at high risk of developing obesity due to complex interplay of factors including antipsychotic medications, restrictions on freedom and poor motivation to healthy lifestyle and physical activities.Aim: To establish the prevalence of obesity and metabolic syndrome (MetS) in a secure forensic psychiatric hospital in the Republic of Ireland (ROI).Methods: We carried out a...