Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep145 | Clinical case reports - Thyroid/Others | ECE2017

Insulinoma masquerading as neurologic disease

Machado Catarina , Tavares Patricia , Monteiro Sara , Rocha Gustavo , Oliveira Maria Joao

Introduction: Insulinomas are the most frequent cause of hypoglycemia and the most common functional endocrine pancreatic tumors. Whipple triad is often present and should alert to the diagnosis.Case report: A 36-year-old male was admitted in the emergency room with loss of consciousness, diaphoresis and blurred vision, and hypoglycemia (50 mg/dl). The patient recalled recurrent symptoms of diaphoresis, tremors and palpitations, sometimes with loss of co...

ea0049ep923 | Paediatric endocrinology | ECE2017

Growth hormone deficiency – the experience of one pediatric endocrinology unit of a Portuguese hospital in the last 5 years

Ferreira Jorge Abreu , Barroso Fabio , Martins Cristiana , Freitas Joana , Cardoso Helena , Oliveira Maria Joao , Borges Teresa

Introduction: Hypopituitarism is a clinical syndrome of deficiency in growth hormone (GHD) production, which can occur isolated or associated with others pituitary defects. GHD has an incidence of 1:4000 to 1:10 000. It may be idiopathic, congenital or acquired.Purpose: Characterize the paediatric population with GHD followed at the Paediatric Endocrinology Unit of our centre and compare the clinical presentation and treatment response of the patients wi...

ea0049ep1211 | Clinical case reports - Thyroid/Others | ECE2017

Thyroid storm subsequent to amiodarone-induced thyrotoxicosis

Machado Catarina , Tavares Patricia , Monteiro Sara , Rocha Gustavo , Oliveira Maria Joao

Introduction: Thyroid storm is a rare medical emergency with high mortality, which usually results from acute exacerbation of hyperthyroidism. Amiodarone is a highly used class III antiarrhythmic drug and amiodarone-induced thyrotoxicosis is an infrequent effect of this medication, whose treatment may be difficult.Case study: A 20-year old male with congenital cardiomyopathy (Fallot tetralogy and Ebstein anomaly), chronically medicated with amiodarone 20...

ea0049ep1351 | Thyroid (non-cancer) | ECE2017

Outcome of radioiodine therapy in patients with hyperthyroidism

Machado Catarina , Tavares Patricia , Monteiro Sara , Rocha Gustavo , Silva Fernando , Oliveira Jose Manuel , Oliveira Maria Joao

Introduction: Radioiodine treatment (RAIT) is an effective definitive treatment for Graves’ Disease (GD) and Toxic Nodular Goiter (TNG). The aim of this study was to analyze demographic and clinical factors affecting the outcome of RAIT in patients with hyperthyroidism.Methods: Retrospective review of patients treated with RAIT for hyperthyroidism. A fixed dose of 10 mCi was administered to patients with GD and 15 mCi to patients with TNG. Treatment...

ea0090ep12 | Adrenal and Cardiovascular Endocrinology | ECE2023

Myocardial Infarction with non-obstructed coronaries: uncommon presentation of pheochromocytoma

Alexandrino Jorge Henrique Carmona , Almeida Ferreira Marta , Ramalho Diogo , Ferreira Diogo Santos , Silva Gualter Santos , Almeida Joao Goncalves , Oliveira Maria Joao

Background: Pheochromocytoma (PHEO) is a rare neuroendocrine tumour, classically presenting with hypertension, palpitations and headaches. Some patients have atypical presentations. We report a case of Myocardial Infarction with non-obstructed coronaries (MINOCA) as the key to unravel the diagnosis of PHEO.Clinical case: A 53-year-old man with type 2 diabetes mellitus and hypertension (under gliclazide MR 60 mg id, bisoprolol 5 mg id, ramipril 5 mg id an...

ea0049ep51 | Adrenal cortex (to include Cushing's) | ECE2017

Education sessions in patients with adrenal insufficiency

Tavora Aldora , Lemos Ema , Duarte Isaura , Sobral Joaquim , Machado Catarina , Tavares Patricia , Rocha Gustavo , Monteiro Sara , Sousa Ana , Rodrigues Pedro , Oliveira Maria Joao

Introduction: Adrenal insufficiency (AI) is a rare and potentially life-threatening disease. The most common causes are primary adrenal insufficiency (Addison’s Disease), due to an adrenocortical disease, and secondary insufficiency, due to disorders of the pituitary gland. Chronic glucocorticoid replacement is vital and patients should be educated about how to act in acute stress situations, in order to avoid adrenal crisis. Taking this into account, we organized educati...

ea0049ep1356 | Thyroid (non-cancer) | ECE2017

TSH receptor stimulating immunoglobulins – performance of an automated immunoassay

Tavares Patricia , Machado Catarina , Pedroso Jose Carlos , Vieira Joana , Rocha Gustavo , Monteiro Sara , Sousa Ana Margarida , Rodrigues Pedro , Lira Agostinho , Oliveira Maria Joao

Introduction: Graves’ disease (GD) hyperthyroidism is caused by autoantibodies against TSH receptor (TRAb). Three varieties of TRAb are now recognized: stimulating (TSI), blocking and neutral antibodies. Current TRAb immunoassays detect and quantify serum immunoglobulins that interact with the TSH receptor but without discriminating their function. An automated immunoassay for the detection and quantification of TSI is available.Objective: Our study...

ea0081p575 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Maturity-onset diabetes of the young in a large portuguese cohort

Santos Monteiro Silvia , Fonseca Liliana , Santos Tiago S. , Assuncao Guilherme , Lopes Ana M. , Duarte Diana B. , Soares Ana Rita , Laranjeira Francisco , Oliveira Maria Joao , Borges Teresa , Cardoso Maria Helena

Introduction: Monogenic forms of diabetes that develop with autosomal dominant inheritance are classically aggregated in the maturity-onset diabetes of the young (MODY) categories. Despite increasing awareness, its true prevalence remains largely underestimated.Aim: o evaluate the clinical and molecular characteristics of patients with MODY.Methodology: This single-center retrospective cohort study enrolled patients with positive g...