Searchable abstracts of presentations at key conferences in endocrinology

ea0032p1026 | Thyroid (non-cancer) | ECE2013

Acute renal failure as the first presentation of severe hypothyroidism

Anil Cuneyd , Oruc Aysegul

Introduction: Renal impairment associated with hypothyroidism without any other clear underlying cause is relatively rare. We report a case with severe hypothyroidism admitted with acute renal failure.Case report: A 72 years old female patient was addmitted to the emergency department with progressively worsening complaints of fatigue, somnolence, and swellings all over her body for the last 3 weeks. Initial laboratory examination revealed acute renal fa...

ea0049ep751 | Calcium & Vitamin D metabolism | ECE2017

The effect of parathyroidectomy on graft function in kidney transplant recipients with persistent hypercalcemia

Oruc Aysegul , Ersoy Alparslan , Oz Gul Ozen , Ersoy Canan

Although serum calcium (Ca), phosphorus and parathyroid hormone (PTH) levels tend to normalize after successful kidney transplantation (KT), persistent hyperparathyroidism (PHPT) can have deleterious effects on graft function. We aimed to evaluate the effect of parathyroidectomy (PTx) on graft function in recipients after KT.Methods: This retrospective study conducted in 319 adult KT recipients. PHPT is defined as serum corrected Ca level >10.2 mg/dl...

ea0056ep50 | Diabetes, Obesity and Metabolism | ECE2018

Diabetes mellitus development secondary to chronic pancreatitis in a kidney transplant recipient

Ersoy Alparslan , Aktas Nimet , Oruc Aysegul , Yildiz Abdulmecit , Ersoy Canan

Acute pancreatitis in kidney transplant recipients is an infrequent complication with complex etiology. However, there was no enough data about chronic pancreatitis after kidney transplantation. Glucose intolerance occurs with some frequency in chronic pancreatitis, but overt diabetes mellitus usually occurs late in the course of the disease. We presented long-term course of a kidney transplant recipient who developed recurrent acute pancreatitis.Case re...

ea0056gp75 | Diabetes Complications | ECE2018

Effects of post-transplant and pre-existing diabetes mellitus on graft function after kidney transplantation

Ersoy Alparslan , Oruc Aysegul , Guney Bahriye , Akgur Suat , Yildiz Abdulmecit , Ersoy Canan

Diabetes mellitus (DM) is one of the most serious comorbidities in kidney transplant recipients. New onset diabetes after kidney transplantation (NODAT) is a common and an important complication following solid organ transplantation. It is associated with poor graft function and increased cardiovascular complications. Therefore, management of hyperglycemia after transplantation is important to reduce diabetes-related risks. We aimed to compare the effects of pre-existing DM an...

ea0056p217 | Calcium & Vitamin D metabolism | ECE2018

The frequencies of persistent hyperparathyroidism and hypercalcemia after kidney transplantation: a single-center experience

Oruc Aysegul , Ersoy Canan , Oz Gul Ozen , Akgur Suat , Cander Soner , Yildiz Abdulmecit , Ersoy Alparslan

Bone mineral disorders usually resolve after successful kidney transplantation. Serum calcium (Ca), phosphorus (P) and parathyroid hormone (PTH) levels tend to normalize within time. Serum Ca levels >10.2 mg/dL and PTH levels >150 pg/mL at 6th−12th months of transplantation is defined as persistent hypercalcemia and persistent hyperparathyroidism (PHPT) in recipients with normal graft function. Reported persistent hypercalcemia prevalence varies in wide range bet...

ea0056p320 | Clinical case reports - Thyroid/Others | ECE2018

Development of fatal lactic acidosis after inadvertent use of metformin in a non-diabetic hemodialysis patient

Akgur Suat , Oruc Aysegul , Yildiz Abdulmecit , Ersoy Canan , Gullulu Mustafa , Ersoy Alparslan

Metformin is considered to be the first choice in the treatment of type 2 diabetes mellitus. Lactic acidosis is a rare life-threatening complication of metformin with approximately 50% overall mortality. Metformin is contraindicated in patients with factors predisposing to lactic acidosis such as impaired renal function (eGFR <30 mL/min). Herein, we present a hemodialysis patient who developed lactic acidosis after inadvertent usage of metformin.Case...

ea0056p434 | Diabetes complications | ECE2018

Analysis of kidney biopsy findings in diabetic patients

Akgur Suat , Oruc Aysegul , Yildiz Abdulmecit , Ersoy Canan , Aytac Vuruskan Berna , Gullulu Mustafa , Ersoy Alparslan

Kidney disease occurs in diabetic patients during disease course in time. Diabetes duration, co-morbid diseases, presence of retinopathy, family history of diabetic nephropathy (DN) predict kidney involvement. Although DN is the initial diagnosis in diabetics with proteinuria, other diseases like primary glomerulonephritis (GN) could be the reason of kidney involvement. DN is increasing in proportion with the increase in diabetes prevalence, and it has been predicted to contin...

ea0056p442 | Diabetes complications | ECE2018

The comparison of the fate of arteriovenous fistula in diabetic and non-diabetic recipients following kidneytransplantation

Ersoy Alparslan , Odman Hikmet Utku , Yolgosteren Atif , Oruc Aysegul , Akgur Suat , Yildiz Abdulmecit , Ersoy Canan

Native arteriovenous fistula (AVF) represents the best vascular approach for chronic hemodialysis. It is difficult to create an AVF in diabetic hemodialysis patients due to atherosclerotic changes in the arteries. Although AVF becomes useless after a successful kidney transplant, there is no accepted policy for preserving or ligating AVF. The aim of this study was to compare the fate of AVFs in diabetic and non-diabetic patients after kidney transplantation.<p class="abste...

ea0056p848 | Pituitary - Clinical | ECE2018

Tolvaptan usage in hyponatremic patients with syndrome of inappropriate secretion of antidiuretic hormone: a single-center experience

Akgur Suat , Oruc Aysegul , Yildiz Abdulmecit , Ersoy Canan , Gullulu Mustafa , Yavuz Mahmut , Dilek Kamil , Ersoy Alparslan

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a disorder of impaired water excretion caused by inability to suppress secretion of antidiuretic hormone. The therapy of SIADH varies with severity of hyponatremia and presence or absence of symptoms. Non-peptide vasopressin receptor antagonists (vaptans) are effective at increasing sodium in euvolemic and hypervolemic states and appear safe. We aimed to evaluate the efficacy of tolvaptan in euvolemic h...

ea0056p991 | Clinical case reports - Thyroid/Others | ECE2018

Tuberculosis abscess resembling thyroiditis

Oruc Aysegul , Akgur Suat , Yildiz Abdulmecit , Ersoy Canan , Gul Ozen Oz , Cander Soner , Ersoy Alparslan

Tuberculosis (TB) infection incidence is still high among solid organ transplant recipients. TB in recipients can manifest several years after transplantation, especially in developing countries. Atypical clinical presentations and extrapulmonary involvement are not uncommon in recipients. Herein, we reported a kidney transplant recipient with TB abscess who admitted with fever and swelling on thyroid gland region.Case: A 57-year old female recipient und...