Endocrine Abstracts

Background: Craniopharyngiomas are rare, relatively benign, slowly growing intracranial tumors originating in pituitary gland embryonic tissue. They may present at any age, with two peaks of occurrence in children and in older adults. Clinical symptoms are the result of mass effects. Treatment options include surgery, radio- and chemotherapy and unfortunately are connected with a high ratio of postoperative pituitary insufficiency.Aim: To present the lon...

Introduction: Paragangliomas (PGL) are rare tumours of neuroendocrine origin. Those localized in urinary bladder account for 10% of all PGL. They arises from chromaffin tissue of the sympathetic nervous system that is embedded in the muscle layer of the bladder wall. Approximately 10% of urinary bladder paragangliomas are malignant.Case presentation: A 76-year-old female presented with a history of haematuria, hypertension, headaches and excessive sweati...

Background: Pituitary stalk lesions (PSL) are various changes located in the pituitary infundibulum. The underlying pathology and exact diagnosis are difficult to establish due to their difficult anatomical locus.Aim: To present the etiological spectrum of pituitary stalk lesions and their clinical and hormonal characteristics on the basis of long term observation in the pediatric/adult endocrinology departments of our university.M...

Background: Hypopituitarism is a condition caused by deficiency in one or multiple pituitary hormones. The disease is associated with various metabolic disorders and decreased quality of life that are particularly marked in patients with childhood onset of the disorder. There are manyfactors influencing the metabolic status of patients such as different treatment modalities (surgery, radiotherapy, chemotherapy) and current supplementation (e.g. steroid or testosterone/estradio...

Background: Pituitary stalk lesions (PSL) is a general term used to describe changes located in the pituitary infundibulum. Special anatomical locus makes the diagnosis difficult to establish. Most of the patients with PSL characterizes with hypopituitarism and multiple metabolic abnormalities.Aim: To present the characteristic of patients with PSL.Methods: We analyzed data of 35 patients (21 M/14 W) with pituitary stalk ...