Searchable abstracts of presentations at key conferences in endocrinology

ea0099oc1.2 | Oral Communications 1: Reproductive and Developmental Endocrinology | ECE2024

Mortality among women with POI, nationwide register based case-control study

Haapakoski Hilla , Silven Heidi , Pesonen Paula , Savukoski Susanna , Niinimaki Maarit

Introduction/Purpose: Despite some evidence that women with premature ovarian insufficiency (POI, loss of ovarian activity<40 years of age) are at risk for diminished life expectancy, large scale population-based studies are still scarce. The evidence on whether hormone replacement therapy (HRT) use decreases the mortality risk among women with POI are lacking. The aim of our study was to explore mortality among women with spontaneous POI and their controls in a large nati...

ea0099rc1.6 | Rapid Communications 1: Reproductive and Developmental Endocrinology | ECE2024

The prevalence of serious autoimmune diseases is increased in women with premature ovarian insufficiency in Finland – A population-based study

Savukoski Susanna , Silven Heidi , Pesonen Paula , Pukkala Eero , Gissler Mika , Suvanto Eila , Ollila Meri-Maija , Niinimaki Maarit

Introduction: Autoimmunity is an important etiological factor of premature ovarian insufficiency (POI, menopause <40 years). It has been estimated that 4-50 % of POI cases are of autoimmune origin. Only a few studies, with sample sizes of dozens to hundreds POI cases, have investigated the prevalence of autoimmune diseases in women with POI. We aimed to assess in an essentially larger data set the prevalence of severe autoimmune diseases treated in tertiary care prior to P...

ea0070aep784 | Reproductive and Developmental Endocrinology | ECE2020

Polycystic ovary syndrome is burdened with a high comorbidity rate and medication use independent of BMI: A longitudinal community based study

Kujanpää Linda , Piltonen Terhi , Arffman Riikka , Pesonen Paula , Morin-Papunen Laure , Tapanainen Juha , Franks Stephen , Järvelin Marjo-Riitta

Objective: To investigate comorbidity rate, symptoms, overall morbidity, medication useand use of health care services among women with polycystic ovary syndrome (PCOS).Design: Community-based prospective cohort study.Patients: Womenreporting oligo/amenorrhea and hirsutism at age 31 and/or PCOS diagnosis by age 46 (n = 280) and controls without PCOS related symptoms or diagnosis (n = 1573) in the Northern ...

ea0099p263 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Risk of type 2 diabetes in 99,892 nordic women with polycystic ovary syndrome and 446,055 controls: national cohort study from Denmark, Finland and Sweden

Glintborg Dorte , Ollila Meri-Maija , Moller Jens-Jakob , Pesonen Paula , Persson Sofia , Elenis Evangelia , Rubin Katrine , Gissler Mika , Andersen Marianne , Sundstrom-Poromaa Inger , Piltonen Terhi

Background: The risk of type 2 diabetes (T2D) in PCOS is associated with BMI, but prospective data regarding risk of T2D in PCOS are limited. We investigated prospective risk of T2D in Nordic women with PCOS compared to controls.Methods: National register-based study in women with PCOS and age-matched controls originating from Denmark (PCOS Denmark, (n=27,016, controls, (n=133,994), Finland (PCOS Finland, (n=20,467, controls, (...