Endocrine Abstracts

Rationale: Grave’s disease (GD) is the most common subtype of autoimmune hyperthyroidism, which can manifest with a variety of extrathyroidal clinical syndromes such as ophthalmopathy, pretibial myxedema (dermopathy), acropathy, cardiomyopathy, and encephalopathy. In very rare instances, GD can also be diagnosed following severe gastrointestinal symptoms such as dysphagia, heartburn, nausea and vomiting. We hereby describe a rare case of GD with digestive symptoms which w...

IntroductionThyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism characterized by the sudden onset of hypokalemia and muscle paralysis. This rare but possible clinical presentation of thyrotoxicosis is significantly more predominant in males of asian descent. The mechanisms of hypokalemia are incompletely understood. The prevailing theories include increased Na-K ATPase pump activity and mutations in genes encoding Kir channels i...