Searchable abstracts of presentations at key conferences in endocrinology

ea0059p101 | Diabetes & cardiovascular | SFEBES2018

Characterisation of diabetes mellitus in turner syndrome – Turner syndrome life course project

Pimblett Antoinette Cameron , Nair Sasha , La Rosa Clementina , Davies Melanie C , Conway Gerard S

Introduction: Diabetes Mellitus (DM) is 2–4 times more common in Turner Syndrome (TS) than karyotype normal females. Diagnosis of DM in TS is usually based on age of presentation and insulin dependency without regard for DM- autoimmunity. Previous research has identified DM associations with the isochromosome and ring chromosome. However, only small numbers of diabetics have been included in reports so far. Here we present preliminary data on DM characterisation in TS.</p...

ea0059p197 | Reproduction | SFEBES2018

Reproductive Life Course Project: Preliminary data from UK Turner Syndrome Pregnancy audit

Burt Elizabeth , Pimblett Antoinette Cameron , Donohoe Mollie , Calanchini Matilde , Morton Claire , Smyth Arlene , Brooke Antoinia , Gleeson Helena , Simpson Helen , Turner Helen E , Davies Melanie C , Conway Gerard S

Turner Syndrome (TS) affects 1:2500 females and is caused by the partial or complete loss of one X chromosome. About 80% of women with TS experience primary amenorrhea and therefore the only option for fertility treatment is ovum donation (OD). The remaining 20% may have the opportunity for a spontaneous pregnancy. Pregnancy in women with TS has been associated with excess obstetric risk such as miscarriage and hypertension. Maternal mortality has been estimated to be 2% risk ...