Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep336 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Studying the care and social pathway of young adults with endocrine and metabolic diseases during transition: The ‘Transend’ cohort

Le Roux Enora , Menesguen Florence , Tejedor Isabelle , Halbron Marine , Popelier Marc , Faucher Pauline , Poitou Christine , Polak Michel , Touraine Philippe

Context: The transition period between pediatric and adult medicine is associated with poor patient outcomes and an important number of patients lost to follow up. Intervention exist but the few published randomized trials do not allow to study long-term patient outcomes nor intervention sustainability in time. Objective. Describe the cohort of patients in adult care who benefit from a new transition program based on case management approach, its activity and follow-up outcome...

ea0090p331 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Exploration of Clinical Improvements Following Setmelanotide in Patients With Bardet-Biedl Syndrome

Haqq Andrea M. , Chung Wendy , Dollfus Helene , Iqbal Anoop , A. Martos-Moreno Gabriel , Poitou Christine , Yanovski Jack A. , Malhotra Sonali , Miller Paul , Yuan Guojun , Forsythe Elizabeth , Clement Karine , Argente Jesus

Background: In patients with Bardet-Biedl syndrome (BBS), signaling impairments in the melanocortin-4 receptor (MC4R) pathway lead to hyperphagia and severe obesity, which negatively impact quality of life (QOL). We evaluated the impact of setmelanotide, an MC4R agonist, on age-appropriate weight-related parameters, hunger, and QOL in a Phase 3 trial of patients with BBS to further characterize clinical benefit in this patient population.Methods: Patient...