Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep1173 | Clinical Cases–Pituitary/Adrenal | ECE2015

Longest survival with central diabetes insipidus; more than 30 years without and 25 years with desmopressin treatment

Ozdemir Didem , Polat Sefika Burcak , Polat Yunus Halil , Ersoy Reyhan , Cakir Bekir

Introduction: Diabetes insipidus (DI) is a disease characterized by excessive thirst, polydipsia and excess diluted urine caused by insufficiency of antidiuretic hormone or renal resistance to its effect. Although it is generally a benign condition, severe hypernatremia and hypertonicity may cause death if water loss is not compensated.Case report: A 72-years-old man admitted to our clinic for routine control. In medical history, he told that when he was...

ea0037ep1234 | Clinical Cases–Pituitary/Adrenal | ECE2015

Hemangiopericytoma associated hypoglycaemia and concomitant secondary adrenal insufficiency

Kiyici Sinem , Topyildiz Figen , Polat Bunyamin , Hunuk Ahmet

Introduction: Hemangiopericytomas (HPC) are rare vascular tumours that may be associated with hypoglycaemia. Here we report a case of HPC with multiple metastases, accompanying severe recurrent hypoglycaemia due to the combination of different aetiologies.Case report: A 21 year-old woman was hospitalised due to loss of consciousness. The patient has been diagnosed as HPC by tibia mass biopsy 1 year ago. Tumour embolization was made several times. On admi...

ea0035p84 | Bone and Osteoporosis | ECE2014

Teriparatide treatment in a patient with severe pregnancy related osteoporosis

Polat Burcak , Evranos Berna , Aydin Cevdet , Ersoy Reyhan , Cakir Bekir

Introduction: Pregnancy or lactation related osteoporosis (PLO) is very rare. It usually occurs in the third trimester or in the early post partum period and manifestations are severe back pain and loss of height due to vertebral fractures. Its etiology is not well understood. Classical treatment is cessation of lactation, calcium and Vit-D supplementation and biphosphanates in chosen cases. All osteoporosis drugs are approved mainly for post-menouposal osteoporosis a...

ea0029p552 | Diabetes | ICEECE2012

The effects of fat distribution and some adipokines on insulin resistance in prediabetic patients

Ekiz Bilir B , Guldiken S , Tuncbilek N , Demir M , Polat A

Introduction: In this study, we aimed to evaluate the effects of fat distribution and some adipokines on insulin resistance (IR) in prediabetic patients.Materials and Methods: cases were divided into three groups according to 75 gr-oral glucose tolerance test (OGTT) results [27 cases impaired fasting glucose (IFG), 36 cases impaired glucose tolerance (IGT) and 24 healthy control subjects]. Serum fasting insulin levels and lipid parameters were measured. ...

ea0020s23.4 | Adrenocortical tumours – pathogenesis and management | ECE2009

Chemotherapy and radiotherapy for adrenocortical carcinoma (ACC)

Fassnacht Martin , Hahner Stefanie , Polat Buelent , Allolio Bruno

ACC is a rare, heterogeneous malignancy with poor prognosis. Data from the German ACC Registry (n=478) indicate a 5-year survival rate of 47%. In addition to mitotane, cytotoxic drugs are standard of care in advanced ACC. The best results have been reported by Berruti et al. for the combination of mitotane with etoposide, doxorubicin and cisplatin with an objective tumor response rate of 49% in 72 patients. A response rate of 36% was published for the combination...

ea0014p403 | (1) | ECE2007

Tumor induced osteomalacia caused by haemangioma of the acetabular surface

Bilen Habib , Akcay Gungor , Polat Pinar , Akcay Mufide , Yildirim Omer

Objective: Tumor induced osteomalacia (TIO) belongs to the group of hypophosphatemic osteomalacias and is induced by a tumor. It is not common disease.Case report: We describe a 34-year-old caucasian man who presented with a 5 year history of diffuse bone pain and muscle weakness. Laboratory investigations showed normal calcium level, low phosphate level between 1.01 mg/dl, and 1.6 mg/dl (reference range: 2.6–5.5 mg/dl), raised alkaline phosphatase ...

ea0099ep679 | Pituitary and Neuroendocrinology | ECE2024

Oral mucosal lesions and dental hygiene assessment in acromegaly patients

Can Cengiz Burak , Polat Sefika , Yildizer Elif , Ates Ihsan

Aim: There is a lack of studies in the literature evaluating the relationship between oral health, oral mucosal lesions, dental hygiene status, and disease prognosis in acromegaly patients. Our study aimed to assess oral mucosa in acromegaly patients, predict dental problems that may develop, correlate oral lesions and mucosal status with patients’ IGF-1 levels, investigate the relationship with the treatment method used, and evaluate the oral mucosal damage caused by con...

ea0049ep237 | Bone & Osteoporosis | ECE2017

Do the surgical outcomes change if the surgeon accompanies the endocrinologist during the preoperative ultrasonography examination?

Kilic Ibrahim , Polat Sefika Burcak , Faki Sevgul , Tokac Mehmet , Ersoy Reyhan , Kilic Mehmet , Cakir Bekir

Introduction: Parathyroid surgical therapy differs because the glands are small and of variable number and location. Although localization studies have improved greatly, we may not reliably determine the number and location of all diseased glands preoperatively. Ultrasonography (US) is the most widely used imaging method. In this study, we aimed to demonstrate how the surgical outcomes change when the surgeon accompanies the endocrinologist during preoperative ultrasonography ...

ea0049ep331 | Clinical case reports - Thyroid/Others | ECE2017

The rare cause of primary hyperparathyroidism: Parathyroid Carcinoma

Bestepe Nagihan , Ozdemir Didem , Polat Sefika Burcak , Evranos Berna , Ersoy Reyhan , Cakir Bekir

Introduction: Parathyroid carcinoma (PC) is a rare endocrine malignancy which accounts for 0.005% of all cancers and less than 1% of primary hyperparathyroidism cases. This uncommon tumor usually occurs during the fifth decade of life, with equal frequency in both sexes, and has an indolent but progressive course. It’s frequently symptomatic and patients may have high values of serum calcium and parathyroid hormone (PTH) with a palpable cervical mass. PC generally occurs ...

ea0049ep1002 | Pituitary - Clinical | ECE2017

Resistant microprolactinoma with partial empty sella

Faki Sevgul , Polat Sefika Burcak , Aydin Cevdet , Ersoy Reyhan , Cakir Bekir

Introduction: Prolactinomas are the most common hormonally active pituitary tumors that account for 40–60% of all pituitary adenomas and are usually successfully treated with dopamine agonists. Surgery or radiotherapy is reserved for drug intolerance/resistance or in neuro-ophthalmological emergencies. We present a patient with refractory microprolactinoma with empty sella treated by transsphenoidal surgery.Case: 42-year-old female patient admitted ...