Endocrine Abstracts

Background: Generalized glucocorticoid-resistance (GCR) is a broad spectrum and heterogeneous syndrome that may be familial or sporadic caused by mutations in glucocorticoid receptor function and signalling. These patients present with hypercortisolism with enlarged adrenals but no Cushing features. Identification of GCR requires extensive investigations.Case report: An 81-year-old thin-built man of South-East Asian orig...

Background: Hyperthyroidism often presents with aberrant liver function. The differential diagnosis of this presentation includes thyrotoxicosis-associated liver dysfunction or antithyroid drug-induced liver dysfunction. We present a case where Propylthiouracil treatment resulted in acute liver failure. Case Presentation: A female patient diagnosed with Grave’s disease in August 2023 initially received carbimazole but discontinued this due to vomiting. S...

Objective: To explore whether assessments recommended by the International PCOS guidelines during the initial consultation for PCOS varied by ethnicity.Methods: This retrospective multi-centre study was conducted from June 2023 to January 2024. All women aged >18 who attended their first consultation in a dedicated PCOS clinic from January 2020 to December 2023 in the UK (n=359), Turkey (n=239), Greece (n=92), and Georgia (...