Endocrine Abstracts

Background: Knowledge of Cranial Diabetes Insipidus (CDI) is poor amongst healthcare professionals. Intra-nasal Desmopressin sprays are often mistaken for pulmonary inhalers, and Diabetes Insipidus mistaken for Diabetes Mellitus, leading to incorrect management and harm. Correct Desmopressin administration and fluid management is paramount in inpatients, especially in reduced conscious states.Aim: To explore Clinicians’ concerns regarding safety iss...

Introduction: Levothyroxine is the first choice treatment for patients with hypothyroidism However, some people would continue to have symptoms of thyroid disease despite biochemical control on levothyroxine. Others might be intolerant to levothyroxine.Aim: The aim of this audit is to evaluate UHL endocrinology practice against local and national guidelines with regards to prescribing and monitoring of liothyronine treatment in 2019.<p class="abstext...

Introduction: The hypercortisolaemic state of Cushing’s syndrome can lead to ophthalmic complications. We present two case reports of rare association of central serous retinopathy (CSR) and Cushing’s syndrome.Case 1: A 46-year-old man presented with gradual deteriorating vision. He was diagnosed with CSR and was referred to the Endocrine department for screening for Cushing’s given suspicious clinical features. Past history included hyper...

Background: Considering the high prevalence of metabolic and mental health issues associated with PCOS, it is important to screen for these routinely in clinic. We aimed to implement a standard approach to ensure we do this in our specialist PCOS clinic.Methods: We introduced a standard ‘PCOS clinic pack’ which included the following documents and data collected for analysis1. Checklist for doctors to e...

Introduction: Opportunistic infections are a recognised complication of severe hypercortisolism. We report a case of Pneumocystis Pneumonia (PCP for formerly named Pneumocystis carinii pneumonia) in patient with ectopic Cushing's syndrome (CS) caused by a metastatic neuroendocrine carcinoma of the lung.Case history: A 61-year old male attended the Acute Medical Unit for investigation and treatment of seve...

Background: Considering the high prevalence of metabolic and mental health issues associated with PCOS, it is important to screen for these routinely in clinic. We aimed to implement a standard approach to ensure we do this in our specialist PCOS clinic.Methods: We introduced a standard ‘PCOS clinic pack’ which included the following documents and data collected for analysis1. Checklist for doctors to e...

Introduction: Opportunistic infections are a recognised complication of severe hypercortisolism. We report a case of Pneumocystis Pneumonia (PCP for formerly named Pneumocystis carinii pneumonia) in patient with ectopic Cushing's syndrome (CS) caused by a metastatic neuroendocrine carcinoma of the lung.Case history: A 61-year old male attended the Acute Medical Unit for investigation and treatment of seve...

Introduction: Hypoglycaemia following bariatric surgery is a recognised complication, secondary to increased incretin secretion to nutrient intake due to altered gut anatomy. It is predominantly postprandial, and usually occurs >6 months postoperatively. We report a case of insulinoma unmasked during the early postoperative period after sleeve gastrectomy (SG).Case presentation: A 49-year old female with severe obesity without diabetes underwent SG. ...

Introduction: Definitive treatment of hyperthyroidism with Radioactive Iodine (RAI) ablation therapy has been associated with weight gain from RAI induced hypothyroidism. Literature on weight data of post-RAI patients following normalisation of thyroid function is equivocal.Objective: We undertook a retrospective study to evaluate the effect of RAI on weight in Hyperthyroid patients in University Hospitals of Leicester NHS Trust (UHL). <p class="abst...

Introduction: Following the recent publication of The Endocrine Society Clinical Practice guideline for Congenital Adrenal Hyperplasia (CAH), we performed an evaluation of the service provided for adults with CAH to assess how well we are meeting the guideline standard and to make recommendations for service improvement.Methods: We performed an audit of adults with CAH under the care of the University Hospitals of Leicester. We undertook a cross-sectiona...