Endocrine Abstracts

Background: The expression of thyroid-specific genes [thyroglobulin (Tg) and sodium iodide symporter (NIS)] is modulated by several cytokines (IL-1, IFNγ, TGF-ß) and it is down-regulated in Hashimoto’s thyroiditis (HT). Also, lymphocytic infiltration and inflammation in HT results in intra-thyroidal accumulation of hyaluronan (HA). During inflammation, HA can be degraded into small fragments, able to up-regulate pro-inflammatory genes by stimulating the toll-li...

ObjectiveWe report a case of acute respiratory syndrome coronavirus 2 (SARSCoV2) pneumonia in which persistently high procalcitonin (PCT) allowed the diagnosis of sporadic medullary thyroid cancer (MTC).MethodsWe describe the history of 43-year-old male with bilateral Sars-Cov-2 pneumoniae, in whom persistent increased PCT despite reduction of C reactive protein lead to investigate other causes of high PCT. S...