Searchable abstracts of presentations at key conferences in endocrinology

ea0090rc9.2 | Rapid Communications 9: Adrenal and Cardiovascular Endocrinology 2 | ECE2023

Frequency of stress dose adjustment and adrenal crisis in children and adults with congenital adrenal hyperplasia

Tschaidse Lea , Wimmer Sophie , Auer Matthias , Lottspeich Christian , F. Nowotny Hanna , Dubinski Ilja , Schmidt Heinrich , Quinkler Marcus , Reisch Nicole

Background: Patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH) require lifelong glucocorticoid replacement therapy, including stress dose adjustment to prevent life-threatening adrenal crises (AC). Previous studies indicate a high incidence of inadequate stress dose adjustment and AC in patients with CAH. The aim of this study was to prospectively assess AC incidence, frequency and details of stress dose adjustment as well as knowledge of the d...

ea0073aep6 | Adrenal and Cardiovascular Endocrinology | ECE2021

Salivary profiles of 11-oxygenated androgens follow a diurnal rhythm in patients with congenital adrenal hyperplasia

Nowotny Hanna F. , Auer Matthias K. , Lottspeich Christian , Schmidt Heinrich , Dubinski Ilja , Bidlingmaier Martin , Adaway Jo , Hawley James , Keevil Brian , Reisch Nicole

BackgroundRoutine biochemical assessment in patients with congenital adrenal hyperplasia (CAH) includes measurement of serum 17–hydroxyprogesterone (17OHP), androstenedione (A4) and testosterone (T) and their metabolites in urine. Several studies have also described 11–oxygenated 19–carbon (110 × C19) steroids as a clinically relevant androgenetic source and highlighted their potential as markers for evaluation of adrenal androgen exc...