Endocrine Abstracts

Introduction: Children undergoing treatment for cancer are prone to several long-term endocrine complications, which can permanently affect bone tissue.Case report: A 25-year-old man was diagnosed with right maxillary sinus rhabdomyosarcoma at the age of 5. He was submitted to chemotherapy – intrathecal methotrexate+prednisolone and i.v. vincristine+actinomycin+ifosfamide – and submaxillary+cervical radiotherapy, 60Gy. At the age of 12, he was ...

Introduction: The increasing risk of thyroid cancer (TC) in patients who underwent radiotherapy is well documented, especially at early ages. In our center, young patients undergoing cancer treatments are referenced to Endocrine Rehabilitation Clinics (ERC). Their risks are initially identified and monitored regularly. We intended to analyze the characteristics and outcomes of patients who developed post-radiotherapy TC.Methods: Medical records of patien...

Introduction: In our practice we’ve been following some oncologic survivors patients with low-low/normal levels of testosterone who are asymptomatic. Aims: to determine the levels of total (TT) and free testosterones (FT) and dihydrotestosterone (DHT) in healthy men, in order to find the reference intervals (RI) adjusted to our population and compare them with those provided by the kit-producers (KP).Methods: We collected blood samples from 125 heal...

Introduction: Current guidelines recommend a single prolactin sampling for the diagnosis of hyperprolactinaemia. Nonetheless, in some patients, prolactin levels may normalize in a subsequent sampling or if prolactin is collected through a venous catheter some time after puncture. We aimed to assess the percentage of patients in which prolactin remained elevated in repeated sampling and to determine the best prolactin cutoff associated with persistent hyperprolactinaemia.<p...