Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep305 | Clinical case reports - Pituitary/Adrenal | ECE2016

Malignant pheocromocytoma – a challenging diagnosis

Topor Liliana , Sirbu Anca

Malignant pheocromocytoma is a rare and problematic disease because it is diagnosed only in the presence of metastases, with no definitive histological or cytological criteria of malignancy. It typically metastasizes to bone, liver, lung and lymph nodes.A 38-year-old woman presented for hypertension (max sBP=160 mmHg), palpitation and dyspnea, with family antecedents of mammary cancer. Clinical examination was normal with the exception of palpable adenop...

ea0084ps1-05-46 | Miscellaneous | ETA2022

Body composition determinants of thyroid function and volume in euthyroid patient with obesity

Sirbu Anca , Busuioc Denisa , Martin Sorina , Barbu Carmen , Fica Simona

The aim of our study was to investigate de relationship between anthropometric and body composition parameters and thyroid function (measured with TSH and free T4), as well as thyroid volume, in patients with obesity.Methods: This is a cross-sectional study including patients with obesity consecutively referred to our tertiary endocrine center for diverse pathologies. TSH and free T4 was measured in all patients and thyroid ultrasound was performed by an...

ea0086p57 | Metabolism, Obesity and Diabetes | SFEBES2022

Parameters associated with neutrophil to lymphocyte ratio in patients with severe obesity

Sirbu Anca , Martin Sorina , Soare Iulia , Manaila Mihaela , Fica Simona

Obesity has been associated with a status of subclinical inflammation. Neutrophil to lymphocyte ratio (NRL) is a widely available and inexpensive inflammatory marker which can be reliable in evaluating the inflammatory status occurring in patients with severe obesity The aim of our study was to investigate the association between NLR and anthropometric and body-composition parameters, in a group of patients with obesityPatients and Methods: 737 patients ...

ea0090ep14 | Adrenal and Cardiovascular Endocrinology | ECE2023

Paraganglioma mimicking a tumor of the liver in an elderly patient

Pana Monica-Mirela , Sirbu Anca , Popa Miruna Maria , Fica Simona

Introduction: Paragangliomas are neuroendocrine tumors that are derived from the embryonic neural crest cells. Because the paraganglia are widespread through the body, paragangliomas can be found in unusual anatomic locations and the diagnosis can be hard to establish. Case presentationWe present the case of an 72 year-old, hypertensive woman who arrived at the hospital for pain in the right hypochondrium. General examination revealed an abdomen without signs of peritoneal irr...

ea0063p274 | Pituitary and Neuroendocrinology 1 | ECE2019

Functioning gonadotroph adenoma in a 46 years old male

Pavel Mihai Lucian , Sirbu Anca Elena , Fica Simona

Introduction: Functioning gonadotroph adenomas (FGA) are adenomas secreting and expressing biologically active gonadotropins and causing distinct clinical manifestations. The vast majority of the immunohistochemically confirmed gonadotroph adenomas are hormonally silent (presenting only with mass effects), clinically FGA’s being very rare; whereas their exact prevalence is not known.Case study: A 46 years old male patient presents to our clinic afte...

ea0041ep843 | Obesity | ECE2016

Hypogonadotropic hypogonadism and obesity, what came first?

Serbanescu Cristina , Nila Alexandra , Sirbu Anca , Fica Simona

Introduction: Morbidly obese patients raise many problems in therapeutic attitude, sometimes associating a cluster of obesity-related abnormalities: hypogonadotropic hypogonadism, metabolic syndrome, respiratory insufficiency, and high risk for cardiovascular disease. These afflictions can be reversed through weight loss, especially in young patients.Case presentation: We present the case of a 41 year old male patient, smoker, with morbid obesity (BMI =6...

ea0040p2 | (1) | ESEBEC2016

Methimazole induced agranulocytosis side effect-not always a bad effect: case report

Soare Iulia , Sirbu Anca , Betivoiu Minodora , Fica Simona

Background: Malignancy and hyperthyroidism used to be considered mutually exclusive, but increased association was observed. These two conditions incidence is variable, ranging between 0 and 9%, Graves’ disease is especially linked to differentiated thyroid carcinoma type.Case presentation: We report the case of a 33 year old, female, smoker, diagnosed with Basedow–Graves disease in may 2015, on methimazole 20 mg/day. She was admitted to our de...

ea0059ep36 | Bone and calcium | SFEBES2018

Low bone mass in young patient with Crohn disease: to treat or not to treat?

Soare Iulia , Sirbu Anca , Tieranu Cristian , Ionescu Mirela , Fica Simona

Introduction: Decreased bone mass is associated with inflammatory bowel disease (IBD), due to multiple factors, including endocrine disturbances, deficits in calcium and vitamin D, malnutrition, drugs (corticosteroids), chronic inflammation. If in older man and postmenopausal women, the treatment is well established, for young patients is not a general consensus.Case report: We report the case of a 20-year-old, male, nonsmoker, diagnosed with Crohn disea...

ea0035p3 | Adrenal cortex | ECE2014

Cardiovascular risk in Cushing's syndrome vs obesity

Martin Sorina , Ionita Andreea , Sirbu Anca , Florea Suzana , Fica Simona

Introduction: Cushing’s syndrome (CS) is associated with central obesity, hypertension, insulin resistance, dyslipidemia, prothrombotic state, manifestations which form a metabolic syndrome. Accelerated vascular senescence, due to metabolic and vascular changes, increases, in CS, the cardiovascular risk and the mortality rates compared to age- and gender-matched population. On the other hand, obesity itself is associated with numerous comorbidities, including hypertension...

ea0070ep22 | Adrenal and Cardiovascular Endocrinology | ECE2020

A case of hypokalemic paralysis in a young hypertensive man

Cristina Pascu Raluca , Maria Popa Miruna , Sirbu Anca , Fica Simona

Background: Hypokalemia can be caused by decreased intake of potassium or by excessive loss of potassium in the urine or through the gastrointestinal tract. Severe and life-threatening hypokalemia is defined by levels below 2.5 mEq/l and can be associated with muscle weakness, cramping, headaches, palpitations, polydipsia and polyuria. Periodic paralysis is a very rare presentation in Caucasians.Case presentation: A 50-year-old Caucasian man, without pre...