Searchable abstracts of presentations at key conferences in endocrinology

ea0025p204 | Growth and development | SFEBES2011

Association between plasma steroid hormone level, growth and obesity in adolescent girls

Matejovicova Barbora , Zatko Tomas , Bezakova Alexandra , Sirotkin Alexander V

The aim of the present study was to examine the role of steroid hormones in control of growth and obesity. We have measured plasma level of progesterone (P4), testosteron (T) and estradiol (E2) in 301 adolescent girls at different stages of their ovarian cycle, and compared they with standard morphometric indexes of their growth and obesity – body height, body mass, abdomen and hip circumstances and waist to hip ratio (WHR). The ovarian cycle-depende...

ea0038p370 | Reproduction | SFEBES2015

Food, drink and medical plants and their molecules can affect female hormones and reproductive functions

Sirotkin Alexander V , Kadasi Attila , Stochmalova Aneta , Alexa Richard , Balazi Andrej , Harrath Abdel Halim

The aim of our studies was to examine the effect of some food, drink and medical plants and their molecules on female ovarian endocrine and other functions in vitro and in vivo. We analysed the effects of plant (green tea, rooibos, ginkgo, flaxseed, chia, yukka) extracts and plant substances (green tea polyphenols, green tea epigallocatechin-3-gallate, curcumin, resveratrol, diadzein and diosgenin) on the release of hormones and markers of proliferation, apop...

ea0034p348 | Steroids | SFEBES2014

The effect of green tea extracts on steroidogenesis, proliferation and apoptosis in ovarian granulosa cells

Kadasi Attila , Maruniakova Nora , Kolesarova Adriana , Stochmalova Aneta , Alexa Richard , Grossmann Roland , Sirotkin Alexander V

The aim of our study was to examine the influence of green tea molecules on basic ovarian functions. For this purpose we have examine the effect of green tea extract, fraction of antioxidants (GTAO) and green tea fraction of polyphenols (GTPP) (at the doses 0, 1, 10, and 100 μg/ml) on proliferation, apoptosis, and steroidogenesis by cultured porcine ovarian granulosa cells. Markers of proliferation (PCNA) and apoptosis (bax) were detected by immunocytochemistry. Secretion...

ea0031p299 | Pituitary | SFEBES2013

The effect of mTOR blockers on japanese quail ovarian granulosa cell functions

Kadasi Attila , Maruniakova Nora , Kolesarova Adriana , Balazi Andrej , Hanusova Emilia , Kotwica Jan , Mai Antonello , Sirotkin Alexander V

The aim of our study was to elucidated the role of mTOR-dependent intracellular signalling pathway in control of ovarian functions. For this purpose, we have examine the effect of three mTOR inhibitors (resveratrol, curcumin and synthetic mTOR blocker MC 2183 – Mai et al. 20051, at the doses 0, 1, 10, 100 μg/ml) on apoptosis and steroidogenesis by cultured Japanese quail ovarian granulosa cells. The release of steroid hormones (progesterone and te...

ea0031p302 | Pituitary | SFEBES2013

Effect of t-2 toxin and combination of t-2 toxin with resveratrol and mc2183 on ovarian cells of japanese quails

Maruniakova Nora , Kadasi Attila , Medvedova Marina , Halenar Marek , Bulla Jozef , Sirotkin Alexander V , Grossmann Roland , Kolesarova Adriana

Occurence of mycotoxins in various food and feed commodities is a worldwide problem. T-2 toxin is one of the most toxic trichothecene mycotoxin, produced mainly by Fusarium species. Poultry belongs to very sensitive species which are very often explored to toxic effects of mycotoxins. The aim of our in vitro studies was to examine secretion activity of ovarian granulossa cells to produce progesterone P4 after T-2 toxin and its combinations with res...