Searchable abstracts of presentations at key conferences in endocrinology

ea0038p171 | Neoplasia, cancer and late effects | SFEBES2015

Acromegaly in association with a bronchial carcinoid tumour

Rys Andrzej , Smith Jamie

Bronchial carcinoid tumours are uncommon pulmonary neoplasms. Manifestation of a bronchial carcinoid with acromegaly secondary to extra-pituitary growth hormone releasing hormone (GHRH) production is rare, but bronchial carcinoid tumours are the most common cause of ectopic GHRH secretion.We report the case of 60 year old female, ex-smoker with hypertension presenting with cough, dyspnoea and right lower lobe opacity on the chest X-ray. Patient was noted...

ea0028p171 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2012

Arterial stiffening and increased pressure wave reflection in HIV recipients of highly active antiretroviral therapy (HAART): the influence of insulin sensitivity, adipokines and autonomic nerve function

Bunce Susan , Sinclair Daivd , Smith Jamie

Background: Treatment of HIV patients with antiretroviral therapies may confer an increased cardiovascular risk, possibly mediated through metabolic perturbations induced by these therapies. We sought to determine whether large arterial stiffening, an early marker and predictor of cardiovascular disease, occurs in HIV recipients of HAART, and if so the plausible mechanisms involved.Methods: In this case-control analysis, 56 HIV subjects (mean age 46 &#17...

ea0091wh7 | Workshop H: Miscellaneous endocrine and metabolic disorders | SFEEU2023

Erdheim Chester disease as a cause of Diabetes Insipidus

Nyi Nyi Htet Soe , Hirwa Kagabo , Smith Jamie

Case Summary: A 53-year-old lady who was normally fit and well, presented with a 3 months history of polydipsia and excessive polyuria up to 13 litres a day. A water deprivation test confirmed a cranial diabetes insipidus, and she was started on desmopressin. Apart from hypothyroidism that was well controlled with levothyroxine replacement, the rest of her pituitary profile was unremarkable for a lady of her age. The rest of her investigations showed persistent increased infla...

ea0038p375 | Reproduction | SFEBES2015

Long-term monitoring of hypogonadal men receiving intramuscular testosterone replacement: a retrospective audit

Rys Andrzej , Candan Jonathan , Cox Sue , Smith Jamie

Background: Intramuscular long acting testosterone injections are widely used, convenient form of androgen replacement in patients with hypogonadism.Aims: To evaluate the long term effects of parenteral long acting testosterone replacement on patients commenced on treatment in years 2006–2014 and adherence to monitoring undertaken by primary care after discharge from specialist service.Method: We reviewed the results of 64 pat...

ea0034p36 | Clinical biochemistry | SFEBES2014

The effects of climate on the incidence of thiazide diuretic induced hyponatraemia in the UK

Redford Christopher , Skinner Thomas , Rys Andrzej , Smith Jamie

Although TIH is a well-established complication of this drug class, the extent of this problem and the serious morbidity that can result is often not appreciated. At our centre, we became aware of three serious cases of TIH over a 2-week period during the ‘heat wave’ in July 2013. In at least one of these cases excessive water drinking was a clear precipitant. We therefore determined the incidence of TIH at our hospital and in particular whether there is a seasonal e...

ea0028p71 | Clinical practice/governance and case reports | SFEBES2012

Long-term remission of postmenopausal ovarian hyperandrogenism may occur following a period of gonadotropin-releasing hormone (GnRH) agonist therapy

Lawrence Carly , Dyke Claire , Cox Sue , Smith Jamie

Excessive ovarian androgen production developing in post-menopausal women can be associated with severe hirsutism and virilisation. In the absence of an identifiable androgen-secreting tumour, medical therapy rather than surgical removal is a potential treatment option. Despite this, the role and outcomes of medical therapy are not well characterised in this context. We present the long-term outcomes of 2 women with postmenopausal ovarian hyperandrogenism, both of whom were tr...

ea0025p188 | Endocrine tumours and neoplasia | SFEBES2011

Clinical outcomes of adrenal incidentalomas over a 3 year period: a retrospective analysis to evaluate a new referral pathway

Dimitropoulos Ioannis , George Roanna , Pickering Emma , Bower Lynne , Waterson Mike , Smith Jamie

Aims: Prior to 2007, there was no agreed guideline at our hospital for the management of adrenal incidentalomas and referrals to our endocrine service were rare. Following evidence-based guidelines, we have developed a local protocol for the assessment of adrenal incidentalomas. We now report clinical outcomes of adrenal incidentaloma patients referred to our endocrine service since its implementation.Methods: Using a retrospective analysis we collected ...