Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep677 | Obesity | ECE2017

Effects of mediterranean diet in obese patients with metabolic syndrome and depression

Dimitrijevic-Sreckovic Vesna , Janeski Hristina , Sreckovic Branko , Soldatovic Ivan , Nesovic Nevena , Vujovic Milica

Introduction: Central obesity is the source of inflammatory factors, causing endothelial dysfunction. In central nervous system, inflammatory factors mediate neurotransmitter metabolism promoting excitotoxicity and increase oxidative stress, and a major clinical symptom is depression. Mediterranean diet (MD) resulted as a good prevention method for depression.Aim: To examine the relationship of depression with abdominal obesity and metabolic syndrome (MS...

ea0049ep678 | Obesity | ECE2017

Visceral obesity in youth followed by decreased testosterone leading to erectile dysfunction and risk of early atherosclerosis

Dimitrijevic-Sreckovic Vesna , Janeski Hristina , Sreckovic Branko , Soldatovic Ivan , Pajovic Milica , Stojanovic Marko

Background: Abdominal obesity, which in fact is a metabolic syndrome (MS), is related to decreased testosterone, insulin resistance (IR), increased inflammatory factors, non-alcoholic fat liver disease (NAFLD) and risk of early atherosclerosis. Elevated inflammatory markers (CRP) may interfere with insulin signal transduction at the neuronal level inducing hypogonadotropic hypogonadism.Objective: To examine testosterone relationship with abdominal obesit...

ea0016p590 | Paediatric endocrinology | ECE2008

Increased hyperinsulinism and insulin resistance, and decreased antioxidant defense, in children and adolescents with pre-metabolic versus metabolic syndromes

Dimitrijevic-Sreckovic Vesna , Sreckovic Branko , Colak Emina , Djordjevic Predrag , Canovic Fadil , Vukosavljevic Dragana , Stojanovic Jecka

Background and aims: The aim was to analyze insulin resistance (IR), glycoregulation disorders, lipid status, C-reactive protein (CRP), plasminogen activator inhibitor (PAI-1) and antioxidant defense in children and adolescents with pre-metabolic (Pre-MS) and metabolic (MS) syndromes.Material and methods: The study included 30 obese individuals (age 10–20 years, body mass index (BMI) or waist circumference (WC) ≥90 percentile). Three of the fo...

ea0049ep367 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2017

Homocystein-significant marker of metabolic syndrome and atherosclerosis risk

Sreckovic Branko , Dimitrijevic-Sreckovic Vesna , Soldatovic Ivan , Janeski Hristina , Janeski Nenad , Gacic Jasna , Sumarac-Dumanovic Mirjana , Mrdovic Igor

Background: Obesity is followed by insulin resistance (IR) and low grade inflammation. In patients with metabolic syndrome (MS) and clinicaly evident vascular complications homocystein values are higher. Hyperhomocysteinemia correlates with hyperinsulinemia and IR, resulting in oxidative stress, which causes endothelial lesions and dysfunction, promoting atherosclerosis and hypertension.Objectives: To examine homocystein levels in patients with and witho...

ea0016p222 | Diabetes and cardiovascular diseases | ECE2008

Atherosclerotic factors, low antioxidant defense and cardiovascular diseases in retinal occlusions and anterior ischemic optic neuropathy

Sreckovic Branko , Dimitrijevic-Sreckovic Vesna , Kosanovic-Jakovic Natalija , Djordjevic Predrag , Colak Emina , Canovic Fadil , Milenkovic Svetislav , Stojanovic Jecka , Resan Mirko

Aim: The aim of the study was to examine the existence of cardiovascular diseases (CVD), atherosclerotic factors and antioxidant defense in patients with central retinal artery and central retinal vein occlusions (CRAO, CRVO) and anterior ischemic optic neuropathy (AION).Materials and Methods: The study included 38 obese individuals with CRAO, CRVO and AION. Glycoregulation disorders were determined by OGTT. Lipid status was determined by spectrophotomet...

ea0011p295 | Diabetes, metabolism and cardiovascular | ECE2006

Metabolic syndrome and insulin sensitivity in early glycoregulation disorders

Vesna Dimitrijevic-Sreckovic VDS , Predrag Djordjevic PDJ , Srdjan Popovic SP , Drasko Gostiljac DG , Fadil Canovic FC , Branko Sreckovic BS , Miroljub Ilic MI , Tanja Novakovic TN , Emina Colak EC , Radmila Obrenovic RO , Gordana Milic GM , Tanja Nisic TN , Visnja Panasiuk VP

Background and Aims: Early glycoregulation disorders, impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) are associated with metabolic syndrome (MS). The aim of this study is: (a) to analyze parameters of insulin sensitivity, glycoregulation, lipid status, microalbuminuria (MI) and homocysteine (HCY) in patients with obesity (I), IFG (II), IGT (III) and newly diagnosed DM type 2 (IV) patients; (b) to determine the percentage of metabolic syndrome at these pati...