Searchable abstracts of presentations at key conferences in endocrinology

ea0014p487 | (1) | ECE2007

Study of aldosterone secretion in patients with essential hypertension using a modified suppression test

Gouli Aggeliki , Androulakis Ioannis , Markou Athina , Ragkou Despoina , Dimitriou Konstantina , Stathopoulou Alexandra , Anagnostou Tilemachos , Kondyli Georgia , Piaditis George

Background: The renin-angiotensin system is important for blood pressure control. Screening and diagnostic tests used so far to diagnose patients with aldosterone related hypertension does not take into consideration the stimulating ACTH effect on aldosterone secretion.Objective: To assess the role of aldosterone in essential hypertension using a modified suppression test, performed under suppressed ACTH levels.Subjects and methods...

ea0014p157 | (1) | ECE2007

Prevalence of autonomous cortisol and aldosterone secretion in patients with a single benign cortical adrenal adenoma after modification of the diagnostic tests

Piaditis George , Kaltsas Gregory , Kounadi Theodora , Markou Athina , Mazarakis Nikos , Gouli Aggeliki , Makras Polyzois , Papadogias Dimitrios , Dimitriou Kostantina , Stathopoulou Alexandra , Kossyvakis Kostantinos , Despoina Ragkou , Kyriakos Vamvakidis , Zografos George , Kontogiorgos George , Chrousos George

Background: The normal cut-offs of screening and diagnostic tests for autonomous aldosterone (AAS) and cortisol (ACS) secretion are poorly defined, mainly due to the presence of adrenal adenomas among those who have served as controls and the stimulating effect of ACTH on aldosterone secretion.Methods: We investigated cortisol and aldosterone secretion in 151 patients with benign cortical adrenal adenomas (BCAA) and in 119 healthy controls with a normal ...