Endocrine Abstracts

Introduction: The occurrence or worsening of thyroid eye disease (TED) after SARS-CoV-2 mRNA vaccines is extremely rare whereas has not been reported following viral vector vaccination. In the region of South-West Greece during the COVID-19 pandemic, a case of de novo appearance of TED referred to the Endocrinology Department of our hospital, following viral vector SARS-COV-2 vaccine.Case report: The patient was a 62-year-old woman, heavy smoker (40 pack...

Background: The renin-angiotensin system is important for blood pressure control. Screening and diagnostic tests used so far to diagnose patients with aldosterone related hypertension does not take into consideration the stimulating ACTH effect on aldosterone secretion.Objective: To assess the role of aldosterone in essential hypertension using a modified suppression test, performed under suppressed ACTH levels.Subjects and methods...

Background: The normal cut-offs of screening and diagnostic tests for autonomous aldosterone (AAS) and cortisol (ACS) secretion are poorly defined, mainly due to the presence of adrenal adenomas among those who have served as controls and the stimulating effect of ACTH on aldosterone secretion.Methods: We investigated cortisol and aldosterone secretion in 151 patients with benign cortical adrenal adenomas (BCAA) and in 119 healthy controls with a normal ...