Searchable abstracts of presentations at key conferences in endocrinology

ea0084op-03-13 | Oral Session 3: Advanced Thyroid Cancer | ETA2022

Thyroid cancer relapse as a challenge to a surgeon: The efficacy of radioguided occult lesion localization (roll) technique

Czarniecka Agnieszka , Wozniak Grzegorz , Zeman Marcin , Kalemba Michal , Wygoda Zbigniew , Chmielik Ewa , Stobiecka Ewa , J. Cortez Alexander , Krajewska Jolanta , Handkiewicz-Junak Daria

Introduction: Reoperation due to recurrent or persistent thyroid cancer (TC) poses a real challenge to a surgeon who must properly estimate the benefit risk-ratio. Radioguided occult lesion localization (ROLL) technique may facilitate the localization and sufficient and safe removal of nonpalpable TC relapse.Aim: To analyze the efficacy of the ROLL technique in reoperation of TC relapse.Material and methods: A retrospective study o...

ea0037ep909 | Thyroid cancer | ECE2015

The risk of thyroid cancer (TC) in a thyroid nodule on the basis of a tertiary reference TC center experience

Blewaska Aleksandra , Sygula Aleksandra , Chmielik Ewa , Stobiecka Ewa , Zembala-Nozynska Ewa , Czarniecka Agnieszka , Sacher Aleksander , Krajewska Jolanta , Kukulska Aleksandra , Jarzab Barbara

A global TC risk in a single thyroid nodule is rather small and ranges between 1 and 11%. However, taking into consideration Bethesda System for Reporting Thyroid Cytopathology TC risk varies between distinct categories: 0–3, 5–15, 15–30, 60–75 and 97–99% for Bethesda class II–VI, respectively. However, these values may differ in a centre, specialized in TC. Therefore, the aim of this study was to evaluate the TC risk in patients referred to a ter...

ea0049ep1420 | Thyroid (non-cancer) | ECE2017

Prognostic value of preoperative serum calcitonin concentration on primary surgery outcomes in medullary thyroid cancer

Gawlik Tomasz , Kukulska Aleksandra , Wygoda Zbigniew , Krajewska Jolanta , Stobiecka Ewa , Czarniecka Agnieszka , Jarzab Barbara

Calcitonin assessment in thyroid diseases is recommended when medullary thyroid cancer (MTC) is suspected in fine needle biopsy, as well as in ‘suspicious for a follicular neoplasm’ class, especially oxyphilic type, in patients with germinal RET proto-oncogene mutation and in nondiagnostic biopsy when no surgical treatment is planned. This assessment is also suggested before any planned thyroid surgery to exclude MTC. Beyond diagnosis confirmation it is also suggeste...

ea0092ps1-06-03 | Thyroid Cancer clinical 1 | ETA2023

Clinical and surgical challenges of local relapse of papillary thyroid carcinoma (PTC)

Czarniecka Agnieszka , Wozniak Grzegorz , Zeman Marcin , Cortez Alexander J. , Stobiecka Ewa , Chmielik Ewa , Oczko-Wojciechowska Malgorzata , Krajewska Jolanta , Handkiewicz-Junak Daria

Aim: The assessment of the disease course and selected clinicopathological factors associated with recurrence risk and the effectiveness of surgical treatment of PTC patients.Material and Methods: The retrospective analysis of 260 PTC patients selected from 403 patients operated on for recurrent thyroid cancer between 2002 and 2018 was performed. All statistical analyses were done using the programming environment R (v. 4.0.2).Resu...

ea0035oc5.5 | Adrenal & Thyroid | ECE2014

Validation of follicular thyroid cancer molecular classifier in fine-needle aspiration biopsy samples

Pfeifer Aleksandra , Bartosz Wojtas , Malgorzata Oczko-Wojciechowska , Aleksandra Kukulska , Agnieszka Czarniecka , Markus Eszlinger , Thomas Musholt , Tomasz Stokowy , Ewa Stobiecka , Jolanta Krajewska , Dagmara Rusinek , Tomasz Tyszkiewicz , Monika Kowal , Michal Jarzab , Steffen Hauptmann , Dariusz Lange , Ralf Paschke , Barbara Jarzab

Introduction: Follicular adenomas (FTA) and carcinomas (FTC) are thyroid tumours that are indistinguishable in the fine needle aspiration biopsy (FNAB). In our previous research we concentrated on post-operative material and developed the classifier, which discriminates the FTC and FTA, based on formalin-fixed paraffin-embedded (FFPE) material. The classifier was based on expression of five genes and gave the promising sensitivity of 71% and specificity of 72%. The aim of the ...