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ea0073aep26 | Adrenal and Cardiovascular Endocrinology | ECE2021

Adrenal steroid profiling in the diagnostics of partial enzyme defects in the adrenals. Establishment of normal cut-off levels using LC-MS/MS

Grethe Åstrøm Ueland , Dahl Sandra R. , Methlie Paal , Husebye Eystein , Thorsby Per Medboe

BackgroundNon-classical congenial adrenal hyperplasia (NCCAH) is an important differential diagnosis in women with acne, hirsutism, menstrual abnormalities and infertility. To diagnose NCCAH can be challenging, and currently used cutoff levels are based on unstandardized immunological assays, no longer in use.ObjectiveDefine LC-MS/MS based cut-off levels for steroid hormones, to improve diagnosis of NCCAH and...

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ea0070ep519 | Thyroid | ECE2020

The Role of Selenium and Iodine on thyroid status in the first trimester of pregnancy

Upmale Sabine , Veisa Vija , Kalere Ieva , Šķesters Andrejs , Makrecka- Kūka Marina , Strēle Ieva , Dambrova Maija , Konrāde Ilze

Introduction: Pregnant women are at risk for selenium deficiency, which is known to maintain adequate function of immune system and thyroprotective enzymes. Same, iodine is an essential micronutrient for thyroid hormone synthesis and important endocrine regulator of early brain development. Our previous study revealed that 81% of pregnant women in Latvia have insufficient levels of iodine. The aim of the present study was to evaluate iodine and selenium supply during pregnancy...

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Endocrine Abstracts

Adrenal steroid profiling in the diagnostics of partial enzyme defects in the adrenals. Establishment of normal cut-off levels using LC-MS/MS

The Role of Selenium and Iodine on thyroid status in the first trimester of pregnancy

BiosciAbstracts