Searchable abstracts of presentations at key conferences in endocrinology

ea0020p30 | Adrenal | ECE2009

Study of hormonal activity and insulin resistance in patients harbouring incidentally discovered bilateral adrenal adenomas

Androulakis Ioannis , Papanastasiou Lambrini , Tsenilklidi Ermioni , Prevoli Anastasia , Kafritsa Paraskevi , Pappa Theodora , Tsiavos Vaios , Piaditis George

Background: Hormonal activity and insulin resistance (IR) in patients with incidentally discovered bilateral adrenal adenomas (BA) has not been evaluated until now. Therefore, we have investigated cortisol and aldosterone secretion and IR in 29 patients with BA, in 113 patients with unilateral adrenal adenomas (UA) and in 89 healthy subjects (C).Methods: All subjects underwent the following investigation: 1) Low dose dexamethasone suppression test (LDDST...

ea0041gp23 | Adrenal (2) | ECE2016

Deterioration of indices of insulin resistance in patients with non-functioning and cortisol secreting adrenal incidentalomas during a long term follow-up

Papanastasiou Labrini , Alexandraki Krystallenia , Fountoulakis Stelios , Kounadi Theodora , Markou Athina , Tsiavos Vaios , Androulakis Ioannis , Samara Christianna , Piaditis George , Kaltsas Gregory

Introduction: Adrenal incidentalomas (AI) with or without concomitant autonomous cortisol secretion can be associated with several metabolic alterations that may lead to increased cardiovascular risk. However, data regarding insulin resistance (IR) during long term follow-up of AI are scarce. The aim was to prospectively investigate the presence and evolution of IR in patients with AI between 2003 and 2014.Methods: Seventy three patients with AI for at l...

ea0022p548 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Evaluation of adrenal morphological and functional alterations in acromegalic patients

Pappa Theodora , Papanastasiou Labrini , Tsiavos Vaios , Tseniklidi Ermioni , Androulakis Ioannis , Tsounas Panagiotis , Roussaki Peggy , Kaltsas Gregory , Piaditis George

Introduction: Acromegaly is well known to induce hypertrophy and hyperplasia in many organs, i.e. thyroid gland, colon, prostate. This action is presumably exerted by the elevated GH and IGF1 levels. In our study, we investigated the alterations of the adrenal glands seen in acromegaly.Aim: To assess the changes in adrenal morphology and functional status in a series of patients with acromegaly.Subjects and methods: Fifty-four acro...

ea0032p46 | Adrenal cortex | ECE2013

Autonomous aldosterone secretion as a significant cause of arterial hypertension: the effectiveness of targeted therapy

Papanastasiou Labrini , Pappa Theodora , Fountoulakis Stelios , Tsounas Panagiotis , Markou Athina , Tsiavos Vaios , Anastasakou Marina , Marakaki Chrisanthi , Malliopoulos Dimosthenis , Kounadi Theodora , Piaditis George

Introduction: The prevalence of autonomous aldosterone secretion (AAS) in hypertensive subjects varies due to the use of various suppression tests and cut-off values. Our aim was to evaluate the prevalence of AAS in hypertensive subjects and test the anti-hypertensive effect of targeted treatment of the renin angiotensin II aldosterone system (RAAS) in AAS subjects.Description of methods/design: We investigated 336 hypertensive subjects with and without ...

ea0099p418 | Adrenal and Cardiovascular Endocrinology | ECE2024

Appraisal of modified tests for the diagnosis and treatment of primary aldosteronism: A single endocrine center experience

Markou Athina , Kaltsas Gregory , Papanastasiou Labrini , Voulgaris Nikolaos , Gouli Aggeliki , Tsiavos Vaios , Gravvanis Christos , Tyfoxylou Ernestini , Vlachou Sofia , Kapsali Chara , Giagourta Irini , Kounadi Theodora , Vamvakidis Kyriakos , Zografos George , Chrousos George , Piaditis George

Introduction: Primary aldosteronism (PA), the most common endocrine cause of secondary hypertension, is generally underdiagnosed using current diagnostic tests.Aim: To present our 14-year experience of prospective studies on the diagnosis, prevalence and treatment of PA.Patients and methods: We studied 992 hypertensive patients and 278 age-, sex- and body mass index – matched controls (194 normotensive and 104 with essential h...